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Circulating MicroRNA Biomarker Studies: Pitfalls and Potential Solutions

Overview of attention for article published in Clinical Chemistry, January 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

patent
3 patents
facebook
1 Facebook page

Citations

dimensions_citation
400 Dimensions

Readers on

mendeley
364 Mendeley
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Title
Circulating MicroRNA Biomarker Studies: Pitfalls and Potential Solutions
Published in
Clinical Chemistry, January 2015
DOI 10.1373/clinchem.2014.221341
Pubmed ID
Authors

Kenneth W Witwer

Abstract

Circulating microRNAs have been proposed as disease biomarkers that may aid in risk assessment, diagnosis, prognosis, and monitoring of treatment response. The perceived opportunity has loomed particularly large in neoplastic disease, where alterations in cancer cells are thought to be reflected in the extracellular space as affected cells release upregulated miRNAs or fail to release apparently downregulated species. Despite the promise of miRNA biomarkers, evaluation of the diagnostic specificity and reproducibility of reported markers suggests that realizing this promise remains a work in progress.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 364 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 <1%
United States 2 <1%
Denmark 2 <1%
Mexico 2 <1%
Brazil 2 <1%
Netherlands 1 <1%
Hungary 1 <1%
Turkey 1 <1%
Belgium 1 <1%
Other 2 <1%
Unknown 348 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 73 20%
Researcher 71 20%
Student > Master 41 11%
Student > Bachelor 36 10%
Student > Doctoral Student 21 6%
Other 54 15%
Unknown 68 19%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 89 24%
Agricultural and Biological Sciences 75 21%
Medicine and Dentistry 58 16%
Neuroscience 9 2%
Engineering 9 2%
Other 43 12%
Unknown 81 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 April 2023.
All research outputs
#3,325,717
of 23,510,717 outputs
Outputs from Clinical Chemistry
#645
of 7,508 outputs
Outputs of similar age
#48,222
of 356,387 outputs
Outputs of similar age from Clinical Chemistry
#16
of 69 outputs
Altmetric has tracked 23,510,717 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,508 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.6. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 356,387 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.