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Mercury contamination in facial skin lightening creams and its health risks to user

Overview of attention for article published in Regulatory Toxicology & Pharmacology: RTP, May 2017
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Title
Mercury contamination in facial skin lightening creams and its health risks to user
Published in
Regulatory Toxicology & Pharmacology: RTP, May 2017
DOI 10.1016/j.yrtph.2017.05.018
Pubmed ID
Authors

Yu Bin Ho, Nor Hidayu Abdullah, Hazwanee Hamsan, Eugenie Sin Sing Tan

Abstract

This study aims to determine concentrations of mercury in facial skin lightening cream according to different price categories (category I: <RM29.99, category II: RM30.00-RM59.99, category III: RM60.00-RM99.99 and category IV: ≥RM100.00) and their potential health risks to users. Prices of skin lightening creams were determined during a preliminary market survey. Thereafter, twenty samples were purchased from various locations such as cosmetic stalls, beauty shops, pharmacies and street vendors based on their stratified price categories. Samples were extracted using microwave digester and analyzed using cold vapor atomic absorption spectrometry (CV-AAS). Non-carcinogenic chronic health risks for application of facial skin lightening cream were calculated using Dermal Absorption Dose (DAD) and Hazard Quotient (HQ). Concentrations of mercury in samples were less than the United States Food and Drug Administration (USFDA) permitted trace levels (<1 ppm) except for one sample from category III which was manufactured in China. Concentrations of mercury in facial skin lightening creams ranged from not detected to 1.13 mg kg(-1). There was no significant association between concentrations of mercury with price categories (p = 0.12). There was no significant non-carcinogenic health risk due to daily application of the facial skin lightening creams based on assumption of 30 years exposure period (HQ < 1).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 121 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 121 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 18 15%
Student > Master 14 12%
Researcher 9 7%
Student > Ph. D. Student 8 7%
Other 6 5%
Other 19 16%
Unknown 47 39%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 15 12%
Chemistry 11 9%
Environmental Science 10 8%
Medicine and Dentistry 5 4%
Biochemistry, Genetics and Molecular Biology 5 4%
Other 19 16%
Unknown 56 46%