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Hypothalamic and Pituitary Function in Brain Death

Overview of attention for article published in Neurologia medico chirurgica, January 1991
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Title
Hypothalamic and Pituitary Function in Brain Death
Published in
Neurologia medico chirurgica, January 1991
DOI 10.2176/nmc.31.881
Pubmed ID
Authors

Hiroyuki YOKOTA, Shouzo NAKAZAWA, Toshirou SHIMURA, Akio KIMURA, Yasuhiro YAMAMOTO, Toshibumi OTSUKA

Abstract

Hypothalamic and pituitary hormone levels were measured in 56 patients meeting the criteria of brain death proposed by the Japanese Ministry of Welfare. Pituitary hormone releasing tests were carried out in 39 patients. In addition, cerebral angiography and transcranial Doppler (TCD) were performed in 13 and six patients, respectively, just after hormone measurements. Serum hypothalamic and pituitary hormone levels were inconsistently high based on the half life time in the presumed absence of cerebral blood flow shown by angiography. The responses to releasing hormones were normal in 16 patients. TCD detected cerebral blood flow in the middle cerebral artery or ophthalmic artery in three patients who showed non-filling on angiography. Postmortem microscopic examination of the hypothalamus and anterior pituitary lobe revealed normal structure and cells intermingled with lytic changes and necrosis. This series suggests that some part of the hypothalamus and hypophysis may still be alive after brain death, although the function of these regions may be clinically insignificant.

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Geographical breakdown

Country Count As %
Netherlands 1 50%
Unknown 1 50%

Demographic breakdown

Readers by professional status Count As %
Professor 2 100%
Readers by discipline Count As %
Agricultural and Biological Sciences 1 50%
Medicine and Dentistry 1 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 January 2013.
All research outputs
#17,636,985
of 25,850,671 outputs
Outputs from Neurologia medico chirurgica
#301
of 541 outputs
Outputs of similar age
#48,832
of 59,690 outputs
Outputs of similar age from Neurologia medico chirurgica
#3
of 3 outputs
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