Title |
Body habitus in heart failure: understanding the mechanisms and clinical significance of the obesity paradox
|
---|---|
Published in |
Future Cardiology, October 2016
|
DOI | 10.2217/fca-2016-0029 |
Pubmed ID | |
Authors |
Parham Parto, Carl J Lavie, Ross Arena, Samantha Bond, Dejana Popovic, Hector O Ventura |
Abstract |
The prevalence of obesity among adults and children worldwide has reached epic proportions and has become a major independent risk factor for the development of heart failure (HF), in addition to a contributor of hypertension and cardiovascular disease. The implications of obesity in the development of HF involve adverse effects on cardiac structure and function. Despite all of this, in the setting of chronic HF, excess body mass is associated with improved clinical outcomes, demonstrating the presence of an obesity paradox. In this review, we will discuss the gender differences, global application, potential mechanisms and role of interventions based on fitness and purposeful weight loss as potential therapeutic strategies. |
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Country | Count | As % |
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United States | 1 | 25% |
Curaçao | 1 | 25% |
United Kingdom | 1 | 25% |
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Demographic breakdown
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Members of the public | 3 | 75% |
Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 59 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 11 | 19% |
Student > Master | 10 | 17% |
Researcher | 6 | 10% |
Lecturer | 3 | 5% |
Student > Ph. D. Student | 3 | 5% |
Other | 5 | 8% |
Unknown | 21 | 36% |
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Immunology and Microbiology | 1 | 2% |
Other | 6 | 10% |
Unknown | 26 | 44% |