Effectiveness of exercise on pain intensity and physical function in patients with knee and hip osteoarthritis: an umbrella and mapping review with meta-meta-analysis
Clovis Varongot-Reille, Laura Barrero-Santiago, Ferran Cuenca-Martínez, Alba Paris-Alemany, Roy La Touche, Aida Herranz-Gómez
Abstract
The aim of this review was to provide a qualitative and quantitative overview of the effects of exercise on pain, physical function, and quality of life for patients with knee and hip osteoarthritis.
This study was an umbrella and mapping review with meta-meta-analysis. Meta-analyses of randomized controlled trials were included. The methodological quality and risk of bias were evaluated using the Modified Quality Assessment Scale for Systematic Reviews and the Risk of Bias in Systematic Reviews tool. The quality of evidence was evaluated using the Physical Activity Guidelines Advisory Committee Grading Criteria.
41 meta-analyses were included, 43.9% of the studies had adequate methodological quality, and 56.1% of the studies had a low risk of bias. Moderate evidence was found that exercise decreases pain intensity (33 meta-analyses; SMD = -0.49; 95% CI -0.56 to -0.42), improves function (19 meta-analyses; SMD = -0.50; 95% CI -0.58 to -0.41), strength (6 meta-analyses; SMD = -0.57; 95% CI -0.70 to -0.44) and quality of life (SMD = -0.36; 95% CI -0.46 to -0.27) for patients with hip and knee osteoarthritis.
Exercise is an effective intervention to decrease pain intensity and improve function in patients with hip and knee osteoarthritis.(PROSPERO, CRD42020221987).
This research output has an Altmetric Attention Score of 34. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 September 2024.
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