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X Demographics
Mendeley readers
Attention Score in Context
| Title |
iPS cells: A source of cardiac regeneration
|
|---|---|
| Published in |
Journal of Molecular & Cellular Cardiology, October 2010
|
| DOI | 10.1016/j.yjmcc.2010.10.026 |
| Pubmed ID | |
| Authors |
Yoshinori Yoshida, Shinya Yamanaka |
| Abstract |
For the treatment of heart failure, a new strategy to improve cardiac function and inhibit cardiac remodeling needs to be established. Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) are pluripotent cells that can differentiate into cell types from all three germ layers both in vitro and in vivo. The therapeutic effect of ES/iPS cell-derived progeny was reported in animal model. Mouse and human somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs) by the transduction of four transcription factors, Oct 3/4, Sox2, Klf4, and c-Myc. However, the low induction efficiency hinders the clinical application of iPS technology, and efforts have been made to improve the reprogramming efficiency. There are variations in the characteristics in ES/iPS cell lines, and the further understanding is necessary for the applications of ES/iPS cell technology. Some improvements were also made in the methods to induce cardiomyocytes from ES/iPS cells efficiently. This review article is focused on generation of iPS cells, cardiomyocyte differentiation from ES/iPS cells, and transplantation of derived cardiomyocytes.This article is part of a special issue entitled, "Cardiovascular Stem Cells Revisited". |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 347 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 3 | <1% |
| United States | 2 | <1% |
| Japan | 2 | <1% |
| Germany | 1 | <1% |
| United Kingdom | 1 | <1% |
| Australia | 1 | <1% |
| Portugal | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 335 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 67 | 19% |
| Researcher | 63 | 18% |
| Student > Master | 50 | 14% |
| Student > Bachelor | 49 | 14% |
| Student > Doctoral Student | 23 | 7% |
| Other | 58 | 17% |
| Unknown | 37 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 141 | 41% |
| Medicine and Dentistry | 64 | 18% |
| Biochemistry, Genetics and Molecular Biology | 51 | 15% |
| Engineering | 19 | 5% |
| Chemistry | 6 | 2% |
| Other | 26 | 7% |
| Unknown | 40 | 12% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 March 2019.
All research outputs
#5,263,464
of 25,728,855 outputs
Outputs from Journal of Molecular & Cellular Cardiology
#368
of 2,625 outputs
Outputs of similar age
#22,861
of 110,473 outputs
Outputs of similar age from Journal of Molecular & Cellular Cardiology
#8
of 25 outputs
Altmetric has tracked 25,728,855 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,625 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 110,473 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.