The data shown below were collected from the profiles of 25 X users who shared this research output. Click here to find out more about how the information was compiled.
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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Oscillatory Control of Factors Determining Multipotency and Fate in Mouse Neural Progenitors
|
|---|---|
| Published in |
Science, October 2013
|
| DOI | 10.1126/science.1242366 |
| Pubmed ID | |
| Authors |
Itaru Imayoshi, Akihiro Isomura, Yukiko Harima, Kyogo Kawaguchi, Hiroshi Kori, Hitoshi Miyachi, Takahiro Fujiwara, Fumiyoshi Ishidate, Ryoichiro Kageyama |
| Abstract |
The basic helix-loop-helix transcription factors Ascl1/Mash1, Hes1, and Olig2 regulate fate choice of neurons, astrocytes, and oligodendrocytes, respectively. These same factors are coexpressed by neural progenitor cells. Here, we found by time-lapse imaging that these factors are expressed in an oscillatory manner by mouse neural progenitor cells. In each differentiation lineage, one of the factors becomes dominant. We used optogenetics to control expression of Ascl1 and found that, although sustained Ascl1 expression promotes neuronal fate determination, oscillatory Ascl1 expression maintains proliferating neural progenitor cells. Thus, the multipotent state correlates with oscillatory expression of several fate-determination factors, whereas the differentiated state correlates with sustained expression of a single factor. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 5 | 20% |
| United States | 1 | 4% |
| United Kingdom | 1 | 4% |
| Spain | 1 | 4% |
| France | 1 | 4% |
| Unknown | 16 | 64% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 18 | 72% |
| Scientists | 6 | 24% |
| Science communicators (journalists, bloggers, editors) | 1 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 832 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 13 | 2% |
| Japan | 7 | <1% |
| France | 4 | <1% |
| United Kingdom | 4 | <1% |
| Italy | 1 | <1% |
| Sweden | 1 | <1% |
| Chile | 1 | <1% |
| Argentina | 1 | <1% |
| China | 1 | <1% |
| Other | 5 | <1% |
| Unknown | 794 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 209 | 25% |
| Researcher | 169 | 20% |
| Student > Master | 101 | 12% |
| Student > Bachelor | 77 | 9% |
| Professor | 41 | 5% |
| Other | 126 | 15% |
| Unknown | 109 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 300 | 36% |
| Biochemistry, Genetics and Molecular Biology | 164 | 20% |
| Neuroscience | 103 | 12% |
| Medicine and Dentistry | 51 | 6% |
| Physics and Astronomy | 25 | 3% |
| Other | 67 | 8% |
| Unknown | 122 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 27. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 November 2022.
All research outputs
#1,459,523
of 25,905,864 outputs
Outputs from Science
#23,584
of 83,404 outputs
Outputs of similar age
#13,063
of 227,189 outputs
Outputs of similar age from Science
#310
of 886 outputs
Altmetric has tracked 25,905,864 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 83,404 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 66.2. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,189 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 886 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.