The data shown below were compiled from readership statistics for 142 Mendeley readers of this research output. Click here to see the associated Mendeley record.
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Mendeley readers
Attention Score in Context
| Title |
Uric Acid and Survival in Chronic Heart Failure
|
|---|---|
| Published in |
Circulation, April 2003
|
| DOI | 10.1161/01.cir.0000065637.10517.a0 |
| Pubmed ID | |
| Authors |
Stefan D. Anker, Wolfram Doehner, Mathias Rauchhaus, Rakesh Sharma, Darrel Francis, Christoph Knosalla, Constantinos H. Davos, Mariantonietta Cicoira, Waqar Shamim, Michel Kemp, Robert Segal, Karl Josef Osterziel, Francisco Leyva, Roland Hetzer, Piotr Ponikowski, Andrew J.S. Coats |
| Abstract |
Serum uric acid (UA) could be a valid prognostic marker and useful for metabolic, hemodynamic, and functional (MFH) staging in chronic heart failure (CHF). For the derivation study, 112 patients with CHF (age 59+/-12 years, peak oxygen consumption [Vo2] 17+/-7 mL/kg per minute) were recruited. In separate studies, we validated the prognostic value of UA (n=182) and investigated the relationship between MFH score and the decision to list patients for heart transplantation (n=120). In the derivation study, the best mortality predicting UA cutoff (at 12 months) was 565 micromol/L (9.50 mg/dL) (independently of age, peak Vo2, left ventricular ejection fraction, diuretic dose, sodium, creatinine, and urea; P<0.0001). In the validation study, UA >or=565 micromol/L predicted mortality (hazard ratio, 7.14; P<0.0001). In 16 patients (from both studies) with UA >or=565 micromol/L, left ventricular ejection fraction <or=25% and peak Vo2 <or=14 mL/kg per min (MFH score 3), 12-month survival was lowest (31%) compared with patients with 2 (64%), 1 (77%), or no (98%, P<0.0001) risk factor. In an independent study, 51% of patients with MFH score 2 and 81% of patients with MFH score 3 were listed for transplantation. The positive predictive value of not being listed for heart transplantation with an MFH score of 0 or 1 was 100%. High serum UA levels are a strong, independent marker of impaired prognosis in patients with moderate to severe CHF. The relationship between serum UA and survival in CHF is graded. MFH staging of patients with CHF is feasible. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 142 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 5 | 4% |
| Researcher | 5 | 4% |
| Student > Bachelor | 4 | 3% |
| Student > Doctoral Student | 4 | 3% |
| Student > Ph. D. Student | 4 | 3% |
| Other | 8 | 6% |
| Unknown | 112 | 79% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 20 | 14% |
| Biochemistry, Genetics and Molecular Biology | 4 | 3% |
| Environmental Science | 1 | <1% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | <1% |
| Psychology | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 114 | 80% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 September 2017.
All research outputs
#8,535,472
of 25,374,647 outputs
Outputs from Circulation
#12,063
of 21,095 outputs
Outputs of similar age
#20,346
of 61,950 outputs
Outputs of similar age from Circulation
#88
of 173 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 21,095 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 31.4. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 61,950 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 173 others from the same source and published within six weeks on either side of this one. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.