Title |
Lupus Pleuritis with Silicotic Nodules in the Parietal Pleura
|
---|---|
Published in |
Internal Medicine, December 2017
|
DOI | 10.2169/internalmedicine.9193-17 |
Pubmed ID | |
Authors |
Kazuo Tsuchiya, Mikio Toyoshima, Atsuki Fukada, Daisuke Akahori, Kazuhito Funai, Takafumi Suda |
Abstract |
A 63-year-old man with occupational exposure to silica presented with cutaneous ulcer, pleuritic pain, and a fever. Laboratory data showed lymphopenia and positive serum antinuclear and anti-DNA antibodies. Computed tomography of the chest showed egg shell-like calcification of the hilar and mediastinal lymph nodes without pulmonary parenchymal involvement of silicosis. A surgical biopsy showed silicotic nodules with surrounding infiltration of lymphocytes and plasma cells in the parietal pleura. With a diagnosis of systemic lupus erythematosus (SLE), systemic corticosteroid therapy was given, which led to the resolution of symptoms and laboratory abnormalities. We discuss the relationship between silica exposure and the development of SLE. |
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Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 27 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Doctoral Student | 11 | 41% |
Researcher | 3 | 11% |
Student > Master | 2 | 7% |
Student > Ph. D. Student | 1 | 4% |
Student > Postgraduate | 1 | 4% |
Other | 1 | 4% |
Unknown | 8 | 30% |
Readers by discipline | Count | As % |
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Sports and Recreations | 2 | 7% |
Nursing and Health Professions | 1 | 4% |
Unspecified | 1 | 4% |
Agricultural and Biological Sciences | 1 | 4% |
Other | 0 | 0% |
Unknown | 8 | 30% |