The data shown below were compiled from readership statistics for 204 Mendeley readers of this research output. Click here to see the associated Mendeley record.
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Mendeley readers
Attention Score in Context
| Title |
RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death
|
|---|---|
| Published in |
Cell, May 1995
|
| DOI | 10.1016/0092-8674(95)90072-1 |
| Pubmed ID | |
| Authors |
Ben Z. Stanger, Philip Leder, Tae-Ho Lee, Emily Kim, Brian Seed |
| Abstract |
Ligation of the extracellular domain of the cell surface receptor Fas/APO-1 (CD95) elicits a characteristic programmed death response in susceptible cells. Using a genetic selection based on protein-protein interaction in yeast, we have identified two gene products that associate with the intracellular domain of Fas: Fas itself, and a novel 74 kDa protein we have named RIP, for receptor interacting protein. RIP also interacts weakly with the p55 tumor necrosis factor receptor (TNFR1) intracellular domain, but not with a mutant version of Fas corresponding to the murine lprcg mutation. RIP contains an N-terminal region with homology to protein kinases and a C-terminal region containing a cytoplasmic motif (death domain) present in the Fas and TNFR1 intracellular domains. Transient overexpression of RIP causes transfected cells to undergo the morphological changes characteristic of apoptosis. Taken together, these properties indicate that RIP is a novel form of apoptosis-inducing protein. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 1% |
| Germany | 2 | <1% |
| Malaysia | 2 | <1% |
| France | 1 | <1% |
| India | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 194 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 52 | 25% |
| Researcher | 38 | 19% |
| Student > Master | 20 | 10% |
| Student > Bachelor | 16 | 8% |
| Professor | 11 | 5% |
| Other | 35 | 17% |
| Unknown | 32 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 78 | 38% |
| Biochemistry, Genetics and Molecular Biology | 41 | 20% |
| Medicine and Dentistry | 13 | 6% |
| Immunology and Microbiology | 9 | 4% |
| Neuroscience | 5 | 2% |
| Other | 20 | 10% |
| Unknown | 38 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 20. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 November 2023.
All research outputs
#1,811,577
of 25,373,627 outputs
Outputs from Cell
#5,231
of 17,169 outputs
Outputs of similar age
#523
of 23,412 outputs
Outputs of similar age from Cell
#2
of 99 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 17,169 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 59.1. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 23,412 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 99 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.