↓ Skip to main content

Antioxidative Activity of Tetrahydrocurcuminoids

Overview of attention for article published in Nippon Nōgeikagaku Kaishi, June 2014
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • Good Attention Score compared to outputs of the same age and source (68th percentile)

Mentioned by

patent
16 patents

Citations

dimensions_citation
212 Dimensions

Readers on

mendeley
66 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Antioxidative Activity of Tetrahydrocurcuminoids
Published in
Nippon Nōgeikagaku Kaishi, June 2014
DOI 10.1271/bbb.59.1609
Pubmed ID
Authors

Toshihiko Osawa, Yasunori Sugiyama, Masanori Inayoshi, Shunro Kawakishi

Abstract

In order to develop a new type of antioxidative compound which has both the phenolic and beta-diketone moiety in the same molecule, we converted three known curcuminoids, curcumin (diferuloylmethane, U1), (4-hydroxy-3-methoxycinnamoyl)methane (U2), and bis-(4-hydroxycinnamoyl)methane (U3), which are the natural antioxidants of Curcuma longa L. (tumeric), to tetrahydrocurcuminoids (THU1, THU2, and THU3, respectively) by hydrogenation, and evaluated their antioxidative activity by using linoleic acid as the substrate in an ethanol/water system. Further, we used the rabbit erythrocyte membrane ghost and rat liver microsome as in vitro systems and determined the antioxidative activity of these curcuminoids. When we evaluated their antioxidative activity by these assays, it was found that THU1 had the strongest antioxidative activity among all curcuminoids in each assay system. THU1 has been reported to be one of the main metabolites of U1 in vivo [Holder et al., Xenobiotica, 8, 761-768 (1978)]. These results suggest that THU1 must play an important role in the antioxidative mechanism of U1 in vivo by converting U1 into THU1.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 2%
Unknown 65 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 12%
Student > Bachelor 8 12%
Student > Master 7 11%
Student > Ph. D. Student 6 9%
Other 4 6%
Other 11 17%
Unknown 22 33%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 15%
Chemistry 10 15%
Biochemistry, Genetics and Molecular Biology 7 11%
Medicine and Dentistry 7 11%
Pharmacology, Toxicology and Pharmaceutical Science 4 6%
Other 6 9%
Unknown 22 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 February 2021.
All research outputs
#5,704,163
of 26,268,316 outputs
Outputs from Nippon Nōgeikagaku Kaishi
#652
of 7,267 outputs
Outputs of similar age
#51,260
of 244,687 outputs
Outputs of similar age from Nippon Nōgeikagaku Kaishi
#385
of 2,853 outputs
Altmetric has tracked 26,268,316 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,267 research outputs from this source. They receive a mean Attention Score of 4.4. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,687 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 2,853 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.