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Magnesium Supplementation Diminishes Peripheral Blood Lymphocyte DNA Oxidative Damage in Athletes and Sedentary Young Man

Overview of attention for article published in Oxidative Medicine & Cellular Longetivity, March 2016
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  • Above-average Attention Score compared to outputs of the same age (53rd percentile)
  • Average Attention Score compared to outputs of the same age and source

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170 Mendeley
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Title
Magnesium Supplementation Diminishes Peripheral Blood Lymphocyte DNA Oxidative Damage in Athletes and Sedentary Young Man
Published in
Oxidative Medicine & Cellular Longetivity, March 2016
DOI 10.1155/2016/2019643
Pubmed ID
Authors

Jelena Petrović, Dušanka Stanić, Gordana Dmitrašinović, Bosiljka Plećaš-Solarović, Svetlana Ignjatović, Bojan Batinić, Dejana Popović, Vesna Pešić

Abstract

Sedentary lifestyle is highly associated with increased risk of cardiovascular disease, obesity, and type 2 diabetes. It is known that regular physical activity has positive effects on health; however several studies have shown that acute and strenuous exercise can induce oxidative stress and lead to DNA damage. As magnesium is essential in maintaining DNA integrity, the aim of this study was to determine whether four-week-long magnesium supplementation in students with sedentary lifestyle and rugby players could prevent or diminish impairment of DNA. By using the comet assay, our study demonstrated that the number of peripheral blood lymphocytes (PBL) with basal endogenous DNA damage is significantly higher in rugby players compared to students with sedentary lifestyle. On the other hand, magnesium supplementation significantly decreased the number of cells with high DNA damage, in the presence of exogenous H2O2, in PBL from both students and rugby players, and markedly reduced the number of cells with medium DNA damage in rugby players compared to corresponding control nonsupplemented group. Accordingly, the results of our study suggest that four-week-long magnesium supplementation has marked effects in protecting the DNA from oxidative damage in both rugby players and in young men with sedentary lifestyle. Clinical trial is registered at ANZCTR Trial Id: ACTRN12615001237572.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 170 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 170 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 31 18%
Student > Master 21 12%
Researcher 15 9%
Student > Ph. D. Student 12 7%
Student > Doctoral Student 8 5%
Other 26 15%
Unknown 57 34%
Readers by discipline Count As %
Medicine and Dentistry 22 13%
Sports and Recreations 20 12%
Nursing and Health Professions 14 8%
Biochemistry, Genetics and Molecular Biology 10 6%
Psychology 8 5%
Other 33 19%
Unknown 63 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 April 2024.
All research outputs
#8,732,105
of 25,769,258 outputs
Outputs from Oxidative Medicine & Cellular Longetivity
#1,114
of 3,667 outputs
Outputs of similar age
#115,156
of 315,230 outputs
Outputs of similar age from Oxidative Medicine & Cellular Longetivity
#24
of 54 outputs
Altmetric has tracked 25,769,258 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,667 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 315,230 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 54 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.