The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Innovative Preparation of Curcumin for Improved Oral Bioavailability
|
|---|---|
| Published in |
Biological and Pharmaceutical Bulletin, January 2011
|
| DOI | 10.1248/bpb.34.660 |
| Pubmed ID | |
| Authors |
Hiroki Sasaki, Yoichi Sunagawa, Kenji Takahashi, Atsushi Imaizumi, Hiroyuki Fukuda, Tadashi Hashimoto, Hiromichi Wada, Yasufumi Katanasaka, Hideaki Kakeya, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto |
| Abstract |
Curcumin is a polyphenol that is commonly used for its perceived health benefits. However, the absorption efficacy of curcumin is too low to exhibit beneficial effects. We have successfully developed a highly absorptive curcumin dispersed with colloidal nano-particles, and named it THERACURMIN. The absorption efficacy of THERACURMIN was investigated and compared with that of curcumin powder. The area under the blood concentration-time curve (AUC) after the oral administration of THERACURMIN was found to be more than 40-fold higher than that of curcumin powder in rats. Then, healthy human volunteers were administered orally 30 mg of THERACURMIN or curcumin powder. The AUC of THERACURMIN was 27-fold higher than that of curcumin powder. In addition, THERACURMIN exhibited an inhibitory action against alcohol intoxication after drinking in humans, as evidenced by the reduced acetaldehyde concentration of the blood. These findings demonstrate that THERACURMIN shows a much higher bioavailability than currently available preparations. Thus, THERACURMIN may be useful to exert clinical benefits in humans at a lower dosage. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 5 | 38% |
| United States | 1 | 8% |
| Canada | 1 | 8% |
| Unknown | 6 | 46% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 12 | 92% |
| Practitioners (doctors, other healthcare professionals) | 1 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 427 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | <1% |
| India | 1 | <1% |
| Italy | 1 | <1% |
| Japan | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 421 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 62 | 15% |
| Student > Master | 58 | 14% |
| Researcher | 55 | 13% |
| Student > Ph. D. Student | 50 | 12% |
| Other | 29 | 7% |
| Other | 69 | 16% |
| Unknown | 104 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 76 | 18% |
| Agricultural and Biological Sciences | 54 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 42 | 10% |
| Biochemistry, Genetics and Molecular Biology | 41 | 10% |
| Chemistry | 28 | 7% |
| Other | 63 | 15% |
| Unknown | 123 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 37. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 March 2024.
All research outputs
#1,175,358
of 26,519,936 outputs
Outputs from Biological and Pharmaceutical Bulletin
#25
of 3,322 outputs
Outputs of similar age
#5,431
of 196,340 outputs
Outputs of similar age from Biological and Pharmaceutical Bulletin
#3
of 102 outputs
Altmetric has tracked 26,519,936 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,322 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 196,340 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 102 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.