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MRSA from Santa Catarina State, Southern Brazil: intriguing epidemiological differences compared to other Brazilian regions

Overview of attention for article published in Brazilian Journal of Infectious Diseases, June 2015
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Title
MRSA from Santa Catarina State, Southern Brazil: intriguing epidemiological differences compared to other Brazilian regions
Published in
Brazilian Journal of Infectious Diseases, June 2015
DOI 10.1016/j.bjid.2015.04.009
Pubmed ID
Authors

Alessandro C.O. Silveira, Gabriela R. Cunha, Juliana Caierão, Caio M. de Cordova, Pedro A. d’Azevedo

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most frequently isolated agents in both nosocomial and community settings. It is a constant challenge for antibacterial therapy. Therefore, it becomes essential to understand the epidemiology of MRSA isolates in the institution and/or region to guide empirical therapy. The objective of this study was to evaluate the epidemiological characteristics of MRSA isolates in the state of Santa Catarina, Brazil, and determine if there is a clonal spread. We evaluated 124 clinical isolates of MRSA obtained from various anatomical sites from patients in the state of Santa Catarina in Southern Brazil. The antimicrobial susceptibility profile was evaluated by disk diffusion and minimum inhibitory concentration (MIC) was determined by Etest and broth macrodilution. SCCmec types were determined by multiplex PCR and the clonal relationship among isolates was assessed by pulsed field gel electrophoresis. Antimicrobials that have demonstrated lower rates of resistance were tetracycline (20.2%), sulfamethoxazole-trimethoprim (20.2%) and chloramphenicol (12.9%). We did not detect any resistance to glycopeptides, daptomycin, linezolid, and tigecycline. SCCmec type III was predominant (54%), followed by type II (21.8%), consistent with other Brazilian studies. Twenty-six clones were observed grouping 72 (58%) isolates and no clonal relationship was observed between our isolates and the major epidemic clones circulating in Brazil. An intriguing distinct MRSA epidemiology was observed in Santa Catarina, compared to other Brazilian regions.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 2%
Unknown 50 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 18%
Researcher 8 16%
Student > Bachelor 7 14%
Student > Ph. D. Student 4 8%
Other 3 6%
Other 8 16%
Unknown 12 24%
Readers by discipline Count As %
Medicine and Dentistry 10 20%
Pharmacology, Toxicology and Pharmaceutical Science 6 12%
Agricultural and Biological Sciences 5 10%
Biochemistry, Genetics and Molecular Biology 4 8%
Immunology and Microbiology 4 8%
Other 9 18%
Unknown 13 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 March 2016.
All research outputs
#20,656,161
of 25,373,627 outputs
Outputs from Brazilian Journal of Infectious Diseases
#543
of 809 outputs
Outputs of similar age
#203,296
of 278,348 outputs
Outputs of similar age from Brazilian Journal of Infectious Diseases
#13
of 22 outputs
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