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Salivary cortisol and α-amylase: subclinical indicators of stress as cardiometabolic risk

Overview of attention for article published in Brazilian Journal of Medical and Biological Research, January 2017
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Title
Salivary cortisol and α-amylase: subclinical indicators of stress as cardiometabolic risk
Published in
Brazilian Journal of Medical and Biological Research, January 2017
DOI 10.1590/1414-431x20165577
Pubmed ID
Authors

S. Cozma, L.C. Dima-Cozma, C.M. Ghiciuc, V. Pasquali, A. Saponaro, F.R. Patacchioli

Abstract

Currently, the potential for cardiovascular (CV) stress-induced risk is primarily based on the theoretical (obvious) side effects of stress on the CV system. Salivary cortisol and α-amylase, produced respectively by the hypothalamus-pituitary-adrenal (HPA) axis and the sympathetic-adrenomedullary (SAM) system during stress response, are still not included in the routine evaluation of CV risk and require additional and definitive validation. Therefore, this article overviews studies published between 2010 and 2015, in which salivary cortisol and α-amylase were measured as stress biomarkers to examine their associations with CV/CMR (cardiometabolic risk) clinical and subclinical indicators. A comprehensive search of PubMed, Web of Science and Scopus electronic databases was performed, and 54 key articles related to the use of salivary cortisol and α-amylase as subclinical indicators of stress and CV/CMR factors, including studies that emphasized methodological biases that could influence the accuracy of study outcomes, were ultimately identified. Overall, the biological impact of stress measured by salivary cortisol and α-amylase was associated with CV/CMR factors. Results supported the use of salivary cortisol and α-amylase as potential diagnostic tools for detecting stress-induced cardiac diseases and especially to describe the mechanisms by which stress potentially contributes to the pathogenesis and outcomes of CV diseases.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 181 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 181 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 26 14%
Student > Master 23 13%
Researcher 15 8%
Student > Doctoral Student 11 6%
Student > Ph. D. Student 11 6%
Other 27 15%
Unknown 68 38%
Readers by discipline Count As %
Medicine and Dentistry 31 17%
Nursing and Health Professions 13 7%
Psychology 12 7%
Biochemistry, Genetics and Molecular Biology 11 6%
Neuroscience 9 5%
Other 30 17%
Unknown 75 41%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 February 2017.
All research outputs
#20,660,571
of 25,382,440 outputs
Outputs from Brazilian Journal of Medical and Biological Research
#901
of 1,254 outputs
Outputs of similar age
#320,195
of 421,709 outputs
Outputs of similar age from Brazilian Journal of Medical and Biological Research
#30
of 63 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,254 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 421,709 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 63 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.