Title |
The Epidemiological Impact of Antimeningococcal B Vaccination in Cuba
|
---|---|
Published in |
Memórias do Instituto Oswaldo Cruz, August 1999
|
DOI | 10.1590/s0074-02761999000400002 |
Pubmed ID | |
Authors |
Antonio Pérez Rodríguez, Félix Dickinson, Alberto Baly, Ramón Martinez |
Abstract |
The incidence of invasive meningococcal disease (IMD) before (1984-1988) and after (1989-1994), a nationwide intervention with VA-MENGOC-BC vaccination started in 1989, was compared. The prevaccination period incidence density (ID> 8.8/10(5) year-person) was higher than the postvaccination ID (ID< 6.5/10(5) year-person). The percentage proportional differences from the start to the end of each period of ID in the vaccinal period was higher (87%) than the prevaccinal (37%) with significant differences among vaccinated groups (< 25 years old). A break-point (Chow test) was confirmed by the decrease in the ID between 1989 and 1990 in children under 1 year old, 5-9, 10-14, 15-19 and 50-54 years. Comparison of ID using maps showed a decrease in IMD in all municipalities during the postvaccination period. These findings support the epidemiological impact of VA-MENGOC-BC vaccination in the reduction of IMD morbidity. |
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Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 15 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 3 | 20% |
Student > Ph. D. Student | 3 | 20% |
Student > Postgraduate | 2 | 13% |
Student > Bachelor | 1 | 7% |
Researcher | 1 | 7% |
Other | 1 | 7% |
Unknown | 4 | 27% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 4 | 27% |
Agricultural and Biological Sciences | 3 | 20% |
Immunology and Microbiology | 2 | 13% |
Nursing and Health Professions | 1 | 7% |
Unknown | 5 | 33% |