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Capillaria hepatica in rats: focal parasitic hepatic lesions and septal fibrosis run independent courses

Overview of attention for article published in Memórias do Instituto Oswaldo Cruz, February 2007
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Title
Capillaria hepatica in rats: focal parasitic hepatic lesions and septal fibrosis run independent courses
Published in
Memórias do Instituto Oswaldo Cruz, February 2007
DOI 10.1590/s0074-02762006000800012
Pubmed ID
Authors

Ana Thereza Gomes, Liliane Monteiro Cunha, Carla Guimarães Bastos, Bruno Frederico Medrado, Bárbara CA Assis, Zilton A Andrade

Abstract

Capillaria hepatica causes two main lesions in the liver of rats: multifocal chronic inflammation, directly related to the presence of disintegrating parasites and their eggs, and a process of systematized septal fibrosis. The comparative behavior of these two lesions was investigated in rats experimentally infected with 600 embryonated eggs, following either corticosteroid treatment or specific antigenic stimulation, in an attempt to understand the relationship between these two lesions, and the pathogenesis of septal fibrosis. The two treatments differently modified the morphological aspects of the focal parasitic-related lesions, but did not interfere with the presentation of diffuse septal fibrosis, although a mild decrease in the degree of fibrosis occurred in corticoid-treated animals. These findings indicate that although the two lesions are C. hepatica induced, they are under different pathogenetic control, the induction of septal fibrosis being triggered during early infection to follow an independent pathway.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 33%
Student > Bachelor 4 27%
Professor 3 20%
Professor > Associate Professor 1 7%
Student > Doctoral Student 1 7%
Other 0 0%
Unknown 1 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 33%
Veterinary Science and Veterinary Medicine 4 27%
Medicine and Dentistry 2 13%
Environmental Science 1 7%
Biochemistry, Genetics and Molecular Biology 1 7%
Other 1 7%
Unknown 1 7%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 September 2019.
All research outputs
#8,533,995
of 25,371,288 outputs
Outputs from Memórias do Instituto Oswaldo Cruz
#320
of 1,502 outputs
Outputs of similar age
#46,364
of 169,905 outputs
Outputs of similar age from Memórias do Instituto Oswaldo Cruz
#5
of 24 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,502 research outputs from this source. They receive a mean Attention Score of 4.6. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 169,905 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.