You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Genetics of homocysteine metabolism and associated disorders
|
|---|---|
| Published in |
Brazilian Journal of Medical and Biological Research, December 2009
|
| DOI | 10.1590/s0100-879x2009007500021 |
| Pubmed ID | |
| Authors |
S. Brustolin, R. Giugliani, T.M. Félix |
| Abstract |
Homocysteine is a sulfur-containing amino acid derived from the metabolism of methionine, an essential amino acid, and is metabolized by one of two pathways: remethylation or transsulfuration. Abnormalities of these pathways lead to hyperhomocysteinemia. Hyperhomocysteinemia is observed in approximately 5% of the general population and is associated with an increased risk for many disorders, including vascular and neurodegenerative diseases, autoimmune disorders, birth defects, diabetes, renal disease, osteoporosis, neuropsychiatric disorders, and cancer. We review here the correlation between homocysteine metabolism and the disorders described above with genetic variants on genes coding for enzymes of homocysteine metabolism relevant to clinical practice, especially common variants of the MTHFR gene, 677C>T and 1298A>C. We also discuss the management of hyperhomocysteinemia with folic acid supplementation and fortification of folic acid and the impact of a decrease in the prevalence of congenital anomalies and a decline in the incidence of stroke mortality. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 25% |
| Unknown | 3 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 248 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Portugal | 1 | <1% |
| Russia | 1 | <1% |
| Cyprus | 1 | <1% |
| Unknown | 244 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 39 | 16% |
| Student > Master | 32 | 13% |
| Researcher | 29 | 12% |
| Student > Ph. D. Student | 24 | 10% |
| Student > Doctoral Student | 16 | 6% |
| Other | 48 | 19% |
| Unknown | 60 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 61 | 25% |
| Biochemistry, Genetics and Molecular Biology | 40 | 16% |
| Agricultural and Biological Sciences | 30 | 12% |
| Nursing and Health Professions | 15 | 6% |
| Psychology | 6 | 2% |
| Other | 31 | 13% |
| Unknown | 65 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 January 2021.
All research outputs
#5,141,226
of 25,374,917 outputs
Outputs from Brazilian Journal of Medical and Biological Research
#142
of 1,254 outputs
Outputs of similar age
#27,574
of 176,905 outputs
Outputs of similar age from Brazilian Journal of Medical and Biological Research
#1
of 8 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,254 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 176,905 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them