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Loss to follow-up in a cohort of HIV-negative men who have sex with men: Project Horizonte

Overview of attention for article published in Revista de Saúde Pública, June 2017
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Title
Loss to follow-up in a cohort of HIV-negative men who have sex with men: Project Horizonte
Published in
Revista de Saúde Pública, June 2017
DOI 10.1590/s1518-8787.2017051006681
Pubmed ID
Authors

Ana Paula Silva, Marília Greco, Maria Arlene Fausto, Mariângela Carneiro

Abstract

The objective of this study is to estimate the attrition rates and evaluate factors associated with loss to follow-up between 1994 and 2011 in an open cohort of HIV-negative men who have sex with men. The Project Horizonte is an open cohort study that aimed to assess the incidence of HIV infection, evaluate the impact of educational interventions, and identify potential volunteers for HIV vaccine trials. The rates of losses to follow-up were estimated for three periods (1994-1999, 2000-2005, and 2006-2011). The variables analyzed were collected in a psychosocial questionnaire. Volunteers who dropped out were compared with the ones who remained in the study using a Cox regression model. A total of 1,197 volunteers were recruited. The median follow-up time in the study (n = 626) was 4.2 years. The median follow-up time for the volunteers who dropped out of the study (n = 571) was 1.46 years. The overall rate of loss to follow-up was 11.6/100 person-years. Attrition rates by period were: 12.60 (1994-1999), 11.80 (2000-2005), and 9.00 (2006-2011) per 100 person-years. Factors associated with losses to follow-up were: age group of 21-30 years old, monthly per capita income of more than six or less than one Brazilian minimum wage, having more than two dependents, report of bisexual practice, and inconsistent use of condoms for receptive anal sex. A slight decrease of the loss to follow-up was observed over time. Higher attrition rates happened in the first three years of follow-up. It is possible that the link of the volunteers were not yet well established. Those who reported inconsistent condom use in receptive anal sex were more likely to leave the study, suggesting an underestimation of the incidence of HIV infection in a cohort population. For greater effectiveness, retention strategies must be reassessed considering the connection between the characteristics of homosexual and bisexual behavior and the motivations to engage in health research.

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Mendeley readers

Mendeley readers

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Geographical breakdown

Country Count As %
Unknown 46 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 10 22%
Student > Master 6 13%
Researcher 4 9%
Student > Ph. D. Student 4 9%
Student > Doctoral Student 2 4%
Other 5 11%
Unknown 15 33%
Readers by discipline Count As %
Unspecified 10 22%
Medicine and Dentistry 9 20%
Nursing and Health Professions 2 4%
Agricultural and Biological Sciences 2 4%
Business, Management and Accounting 1 2%
Other 4 9%
Unknown 18 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 July 2017.
All research outputs
#23,689,447
of 26,367,306 outputs
Outputs from Revista de Saúde Pública
#1,019
of 1,170 outputs
Outputs of similar age
#293,932
of 334,374 outputs
Outputs of similar age from Revista de Saúde Pública
#23
of 27 outputs
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So far Altmetric has tracked 1,170 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.