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Title |
Smoking decreases the response of human lung macrophages to double-stranded RNA by reducing TLR3 expression
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Published in |
Respiratory Research, March 2013
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DOI | 10.1186/1465-9921-14-33 |
Pubmed ID | |
Authors |
Jill C Todt, Christine M Freeman, Jeanette P Brown, Joanne Sonstein, Theresa M Ames, Alexandra L McCubbrey, Fernando J Martinez, Stephen W Chensue, James M Beck, Jeffrey L Curtis |
Abstract |
Cigarette smoking is associated with increased frequency and duration of viral respiratory infections, but the underlying mechanisms are incompletely defined. We investigated whether smoking reduces expression by human lung macrophages (Mø) of receptors for viral nucleic acids and, if so, the effect on CXCL10 production. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 5 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 60% |
Scientists | 2 | 40% |
Mendeley readers
The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | 2% |
Unknown | 54 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 10 | 18% |
Researcher | 7 | 13% |
Student > Ph. D. Student | 6 | 11% |
Student > Master | 6 | 11% |
Student > Doctoral Student | 4 | 7% |
Other | 9 | 16% |
Unknown | 13 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 11 | 20% |
Agricultural and Biological Sciences | 9 | 16% |
Immunology and Microbiology | 8 | 15% |
Biochemistry, Genetics and Molecular Biology | 7 | 13% |
Nursing and Health Professions | 2 | 4% |
Other | 4 | 7% |
Unknown | 14 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 106. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 February 2024.
All research outputs
#396,562
of 25,371,288 outputs
Outputs from Respiratory Research
#29
of 3,062 outputs
Outputs of similar age
#2,609
of 208,668 outputs
Outputs of similar age from Respiratory Research
#1
of 40 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,062 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 208,668 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 40 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.