Possible underlying #brain-pathophysiological mechanisms in #Parkinson’s Disease patients with Excessive Daytime Sleepiness. https://t.co/jjFhTe49y9
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https://t.co/nOoFW1f9Jo "Accordingly, altered wake-promoting nerve nuclei and neurotransmitter systems in PD patients are highlighted to providing clues for identifying EDS-causing targets in the sleep and wake cycles."
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https://t.co/nOoFW1f9Jo "More importantly, degeneration of wake-promoting nuclei owing to primary neurodegenerative process of PD is the underlying pathogenesis of EDS."
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https://t.co/nOoFW1f9Jo "It has attracted much attention due to high morbidity, poor quality of life, increased risk for accidents, obscure mechanisms, comorbidity with PD and limited therapeutic approaches."