Title |
Sesame allergy: current perspectives
|
---|---|
Published in |
Journal of Asthma and Allergy, April 2017
|
DOI | 10.2147/jaa.s113612 |
Pubmed ID | |
Authors |
Adil Adatia, Ann Elaine Clarke, Yarden Yanishevsky, Moshe Ben-Shoshan |
Abstract |
Sesame is an important global allergen affecting ~0.1% of the North American population. It is a major cause of anaphylaxis in the Middle East and is the third most common food allergen in Israel. We conducted a systematic review of original articles published in the last 10 years regarding the diagnosis and management of sesame allergy. Skin prick testing appears to be a useful predictor of sesame allergy in infants, although data are less consistent in older children and adults. The diagnostic capacity of serum-specific immunoglobulin E is poor, especially in studies that used oral food challenges to confirm the diagnosis. Double-blind, placebo-controlled food challenge thus remains the diagnostic gold standard for sesame allergy. The cornerstone of sesame allergy management is allergen avoidance, though accidental exposures are common and patients must be prepared to treat the consequent reactions with epinephrine. Novel diagnostic and treatment options such as component-resolved diagnostics, basophil activation testing, and oral immunotherapy are under development but are not ready for mainstream clinical application. |
X Demographics
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Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 6 | 25% |
Romania | 3 | 13% |
United States | 3 | 13% |
Netherlands | 2 | 8% |
Spain | 1 | 4% |
Korea, Republic of | 1 | 4% |
Unknown | 8 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 14 | 58% |
Practitioners (doctors, other healthcare professionals) | 5 | 21% |
Scientists | 4 | 17% |
Science communicators (journalists, bloggers, editors) | 1 | 4% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 105 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 15 | 14% |
Researcher | 10 | 10% |
Student > Master | 10 | 10% |
Student > Bachelor | 10 | 10% |
Other | 8 | 8% |
Other | 16 | 15% |
Unknown | 36 | 34% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 19 | 18% |
Agricultural and Biological Sciences | 12 | 11% |
Biochemistry, Genetics and Molecular Biology | 10 | 10% |
Nursing and Health Professions | 5 | 5% |
Immunology and Microbiology | 5 | 5% |
Other | 14 | 13% |
Unknown | 40 | 38% |