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Mendeley readers
Chapter title |
Dimerization Assessment of Epithelial Growth Factor Family of Receptor Tyrosine Kinases by Using Cross-Linking Reagent
|
---|---|
Chapter number | 6 |
Book title |
ErbB Receptor Signaling
|
Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-7219-7_6 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7218-0, 978-1-4939-7219-7
|
Authors |
Hamid Maadi, Babak Nami, Zhixiang Wang |
Abstract |
Dimerization of the epithelial growth factor (EGF) family of receptor tyrosine kinases is a crucial step for activation of these receptors. Different chemicals such as BS(3) and DSS have been introduced to covalently bind the interacting receptors and fix the dimers. Unique properties of BS(3) including higher water solubility and membrane impermeability make it suitable for assessing receptor-receptor interactions in live cells. In this protocol, we aim to explain a method to evaluate the dimerization of EGF receptors family using BS(3) as a cross-linker reagent. |
Mendeley readers
The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 6 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 1 | 17% |
Researcher | 1 | 17% |
Other | 1 | 17% |
Unknown | 3 | 50% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 1 | 17% |
Chemistry | 1 | 17% |
Unknown | 4 | 67% |