Chapter title |
Menopause, Estrogens, and Glucose Homeostasis in Women
|
---|---|
Chapter number | 11 |
Book title |
Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity
|
Published in |
Advances in experimental medicine and biology, January 2017
|
DOI | 10.1007/978-3-319-70178-3_11 |
Pubmed ID | |
Book ISBNs |
978-3-31-970177-6, 978-3-31-970178-3
|
Authors |
Franck Mauvais-Jarvis |
Abstract |
Randomized trials suggest that menopausal hormone therapy (MHT) prevents type 2 diabetes. Still, the mechanisms of these antidiabetic effects are a matter of controversy. This chapter provides an analysis of epidemiological and clinical evidence and proposes a mechanism for the effect of menopause and MHT on type 2 diabetes development and prevention. It discusses the beneficial role of estradiol on glucose homeostasis that is lost at menopause and improved by MHT, which delays type 2 diabetes. This chapter aims to reconcile differences among studies of the effect of menopause and MHT formulations on type 2 diabetes and argues that discrepancies arise from physiological differences in methods used to assess glucose homeostasis. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 31 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 4 | 13% |
Student > Ph. D. Student | 4 | 13% |
Student > Doctoral Student | 3 | 10% |
Researcher | 3 | 10% |
Professor | 1 | 3% |
Other | 3 | 10% |
Unknown | 13 | 42% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 7 | 23% |
Medicine and Dentistry | 5 | 16% |
Agricultural and Biological Sciences | 4 | 13% |
Nursing and Health Professions | 1 | 3% |
Social Sciences | 1 | 3% |
Other | 1 | 3% |
Unknown | 12 | 39% |