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The Grass Might Be Greener: Medical Marijuana Patients Exhibit Altered Brain Activity and Improved Executive Function after 3 Months of Treatment

Overview of attention for article published in Frontiers in Pharmacology, January 2018
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#26 of 20,468)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

news
19 news outlets
blogs
2 blogs
twitter
281 X users
facebook
17 Facebook pages
reddit
1 Redditor

Citations

dimensions_citation
57 Dimensions

Readers on

mendeley
127 Mendeley
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Title
The Grass Might Be Greener: Medical Marijuana Patients Exhibit Altered Brain Activity and Improved Executive Function after 3 Months of Treatment
Published in
Frontiers in Pharmacology, January 2018
DOI 10.3389/fphar.2017.00983
Pubmed ID
Authors

Staci A. Gruber, Kelly A. Sagar, Mary K. Dahlgren, Atilla Gonenc, Rosemary T. Smith, Ashley M. Lambros, Korine B. Cabrera, Scott E. Lukas

Abstract

The vast majority of states have enacted full or partial medical marijuana (MMJ) programs, causing the number of patients seeking certification for MMJ use to increase dramatically in recent years. Despite increased use of MMJ across the nation, no studies thus far have examined the specific impact of MMJ on cognitive function and related brain activation. In the present study, MMJ patients seeking treatment for a variety of documented medical conditions were assessed prior to initiating MMJ treatment and after 3 months of treatment as part of a larger longitudinal study. In order to examine the effect of MMJ treatment on task-related brain activation, MMJ patients completed the Multi-Source Interference Test (MSIT) while undergoing functional magnetic resonance imaging (fMRI). We also collected data regarding conventional medication use, clinical state, and health-related measures at each visit. Following 3 months of treatment, MMJ patients demonstrated improved task performance accompanied by changes in brain activation patterns within the cingulate cortex and frontal regions. Interestingly, after MMJ treatment, brain activation patterns appeared more similar to those exhibited by healthy controls from previous studies than at pre-treatment, suggestive of a potential normalization of brain function relative to baseline. These findings suggest that MMJ use may result in different effects relative to recreational marijuana (MJ) use, as recreational consumers have been shown to exhibit decrements in task performance accompanied by altered brain activation. Moreover, patients in the current study also reported improvements in clinical state and health-related measures as well as notable decreases in prescription medication use, particularly opioids and benzodiapezines after 3 months of treatment. Further research is needed to clarify the specific neurobiologic impact, clinical efficacy, and unique effects of MMJ for a range of indications and how it compares to recreational MJ use.

X Demographics

X Demographics

The data shown below were collected from the profiles of 281 X users who shared this research output. Click here to find out more about how the information was compiled.
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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 127 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 127 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 13%
Student > Bachelor 16 13%
Researcher 13 10%
Student > Doctoral Student 12 9%
Student > Master 12 9%
Other 29 23%
Unknown 29 23%
Readers by discipline Count As %
Medicine and Dentistry 21 17%
Psychology 20 16%
Neuroscience 12 9%
Biochemistry, Genetics and Molecular Biology 6 5%
Pharmacology, Toxicology and Pharmaceutical Science 6 5%
Other 23 18%
Unknown 39 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 376. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 May 2023.
All research outputs
#88,034
of 26,429,244 outputs
Outputs from Frontiers in Pharmacology
#26
of 20,468 outputs
Outputs of similar age
#2,087
of 457,400 outputs
Outputs of similar age from Frontiers in Pharmacology
#1
of 271 outputs
Altmetric has tracked 26,429,244 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 20,468 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 457,400 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 271 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.