| Chapter title |
Tumor Immunology
|
|---|---|
| Chapter number | 4 |
| Book title |
Tumor Immunology
|
| Published in |
Methods in molecular biology, January 2016
|
| DOI | 10.1007/978-1-4939-3338-9_4 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-3336-5, 978-1-4939-3338-9
|
| Authors |
Di Lullo, Giulia, De Monte, Lucia, Doglioni, Claudio, Protti, Maria Pia, Giulia Di Lullo, Lucia De Monte, Claudio Doglioni, Maria Pia Protti |
| Editors |
Attilio Bondanza, Monica Casucci |
| Abstract |
CD4(+) T cells comprise a significant portion of tumor-infiltrating lymphocytes. Different subsets of CD4(+) T cells exist and they exert different effector functions in tumor immunity depending on the cytokines produced going from antitumor to pro-tumor. Methods that use small aliquots of cells to identify ex vivo the frequency and functional orientation of tumor-specific CD4(+) T cells in the blood and visualization of the presence of different CD4(+) T cell subsets and their localization at the tumor site are valuable tools to determine their clinical impact in neoplastic diseases. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 5 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 3 | 60% |
| Student > Bachelor | 1 | 20% |
| Other | 1 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 3 | 60% |
| Immunology and Microbiology | 1 | 20% |
| Neuroscience | 1 | 20% |