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Stem Cells From the Apical Papilla (SCAP) as a Tool for Endogenous Tissue Regeneration

Overview of attention for article published in Frontiers in Bioengineering and Biotechnology, July 2018
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

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1 blog
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Citations

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88 Dimensions

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129 Mendeley
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Title
Stem Cells From the Apical Papilla (SCAP) as a Tool for Endogenous Tissue Regeneration
Published in
Frontiers in Bioengineering and Biotechnology, July 2018
DOI 10.3389/fbioe.2018.00103
Pubmed ID
Authors

Ola A. Nada, Rania M. El Backly

Abstract

Stem cells extracted from developing tissues possibly exhibit not only unique but also superior traits against their developed counterparts. Indeed, stem cells from the apical papilla (SCAP); a unique group of dental stem cells related to developing roots have been shown to be a promising tool for regenerative endodontic procedures and regeneration in general. Studies have characterized the phenotypic traits as well as other regenerative potentials of these cells. Specific sub-populations have been highlighted as well as their neurogenic and angiogenic properties. Nevertheless, in light of the previously discussed features and potential applications of SCAP, there is still much to understand and a lot of information to unravel. The current review will discuss the role of specific markers for detection of different functional populations of SCAP; including CD146 and STRO-1, as well as their true multilineage differentiation potential. In particular, the role of the secretome in association with paracrine signaling in inflammatory microenvironments is also tackled. Additionally, the role of SCAP both in vitro and in vivo during regenerative approaches and in response to different growth factors and biologic scaffolds is highlighted. Finally, this review will shed light on current knowledge regarding the clinical translational potential of SCAP and elucidate possible areas for future research applications.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 129 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 129 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 20 16%
Student > Bachelor 13 10%
Researcher 12 9%
Student > Ph. D. Student 12 9%
Student > Doctoral Student 9 7%
Other 14 11%
Unknown 49 38%
Readers by discipline Count As %
Medicine and Dentistry 45 35%
Biochemistry, Genetics and Molecular Biology 11 9%
Agricultural and Biological Sciences 7 5%
Nursing and Health Professions 4 3%
Unspecified 2 2%
Other 6 5%
Unknown 54 42%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 December 2019.
All research outputs
#3,845,717
of 23,096,849 outputs
Outputs from Frontiers in Bioengineering and Biotechnology
#521
of 6,783 outputs
Outputs of similar age
#74,628
of 329,806 outputs
Outputs of similar age from Frontiers in Bioengineering and Biotechnology
#13
of 46 outputs
Altmetric has tracked 23,096,849 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,783 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,806 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 46 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.