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Cancer and Thrombosis: The Platelet Perspective

Overview of attention for article published in Frontiers in Cell and Developmental Biology, January 2017
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (74th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

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11 X users
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1 Facebook page

Citations

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98 Dimensions

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136 Mendeley
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Title
Cancer and Thrombosis: The Platelet Perspective
Published in
Frontiers in Cell and Developmental Biology, January 2017
DOI 10.3389/fcell.2016.00147
Pubmed ID
Authors

Claire K. S. Meikle, Clare A. Kelly, Priyanka Garg, Leah M. Wuescher, Ramadan A. Ali, Randall G. Worth

Abstract

Platelets are critical to hemostatic and immunological function, and are key players in cancer progression, metastasis, and cancer-related thrombosis. Platelets interact with immune cells to stimulate anti-tumor responses and can be activated by immune cells and tumor cells. Platelet activation can lead to complex interactions between platelets and tumor cells. Platelets facilitate cancer progression and metastasis by: (1) forming aggregates with tumor cells; (2) inducing tumor growth, epithelial-mesenchymal transition, and invasion; (3) shielding circulating tumor cells from immune surveillance and killing; (4) facilitating tethering and arrest of circulating tumor cells; and (5) promoting angiogenesis and tumor cell establishment at distant sites. Tumor cell-activated platelets also predispose cancer patients to thrombotic events. Tumor cells and tumor-derived microparticles lead to thrombosis by secreting procoagulant factors, resulting in platelet activation and clotting. Platelets play a critical role in cancer progression and thrombosis, and markers of platelet-tumor cell interaction are candidates as biomarkers for cancer progression and thrombosis risk.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 136 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 136 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 23 17%
Researcher 18 13%
Student > Bachelor 14 10%
Student > Master 13 10%
Other 11 8%
Other 28 21%
Unknown 29 21%
Readers by discipline Count As %
Medicine and Dentistry 31 23%
Biochemistry, Genetics and Molecular Biology 24 18%
Agricultural and Biological Sciences 22 16%
Pharmacology, Toxicology and Pharmaceutical Science 8 6%
Immunology and Microbiology 6 4%
Other 10 7%
Unknown 35 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2019.
All research outputs
#6,547,539
of 25,925,760 outputs
Outputs from Frontiers in Cell and Developmental Biology
#1,481
of 10,595 outputs
Outputs of similar age
#108,648
of 425,125 outputs
Outputs of similar age from Frontiers in Cell and Developmental Biology
#5
of 33 outputs
Altmetric has tracked 25,925,760 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 10,595 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 425,125 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.