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The TOR Signaling Pathway in Spatial and Temporal Control of Cell Size and Growth

Overview of attention for article published in Frontiers in Cell and Developmental Biology, June 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#35 of 9,099)
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

news
9 news outlets
twitter
3 X users

Citations

dimensions_citation
56 Dimensions

Readers on

mendeley
134 Mendeley
citeulike
1 CiteULike
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Title
The TOR Signaling Pathway in Spatial and Temporal Control of Cell Size and Growth
Published in
Frontiers in Cell and Developmental Biology, June 2017
DOI 10.3389/fcell.2017.00061
Pubmed ID
Authors

Suam Gonzalez, Charalampos Rallis

Abstract

Cell size is amenable by genetic and environmental factors. The highly conserved nutrient-responsive Target of Rapamycin (TOR) signaling pathway regulates cellular metabolic status and growth in response to numerous inputs. Timing and duration of TOR pathway activity is pivotal for both cell mass built up as well as cell cycle progression and is controlled and fine-tuned by the abundance and quality of nutrients, hormonal signals, growth factors, stress, and oxygen. TOR kinases function within two functionally and structurally discrete multiprotein complexes, TORC1 and TORC2, that are implicated in temporal and spatial control of cell size and growth respectively; however, recent data indicate that such functional distinctions are much more complex. Here, we briefly review roles of the two complexes in cellular growth and cytoarchitecture in various experimental model systems.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 134 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 134 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 23 17%
Researcher 14 10%
Student > Bachelor 11 8%
Student > Master 11 8%
Student > Doctoral Student 8 6%
Other 14 10%
Unknown 53 40%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 38 28%
Agricultural and Biological Sciences 23 17%
Medicine and Dentistry 5 4%
Chemistry 3 2%
Immunology and Microbiology 2 1%
Other 7 5%
Unknown 56 42%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 78. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 October 2019.
All research outputs
#468,027
of 22,979,862 outputs
Outputs from Frontiers in Cell and Developmental Biology
#35
of 9,099 outputs
Outputs of similar age
#11,147
of 317,348 outputs
Outputs of similar age from Frontiers in Cell and Developmental Biology
#1
of 29 outputs
Altmetric has tracked 22,979,862 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,099 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 317,348 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.