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Mitochondrial Tethers and Their Impact on Lifespan in Budding Yeast

Overview of attention for article published in Frontiers in Cell and Developmental Biology, January 2018
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3 X users

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Title
Mitochondrial Tethers and Their Impact on Lifespan in Budding Yeast
Published in
Frontiers in Cell and Developmental Biology, January 2018
DOI 10.3389/fcell.2017.00120
Pubmed ID
Authors

Wolfgang M. Pernice, Theresa C. Swayne, Istvan R. Boldogh, Liza A. Pon

Abstract

Tethers that link mitochondria to other organelles are critical for lipid and calcium transport as well as mitochondrial genome replication and fission of the organelle. Here, we review recent advances in the characterization of interorganellar mitochondrial tethers in the budding yeast, Saccharomyces cerevisiae. We specifically focus on evidence for a role for mitochondrial tethers that anchor mitochondria to specific regions within yeast cells. These tethering events contribute to two processes that are critical for normal replicative lifespan: inheritance of fitter mitochondria by daughter cells, and retention of a small pool of higher-functioning mitochondria in mother cells. Since asymmetric inheritance of mitochondria also occurs in human mammary stem-like cells, it is possible that mechanisms underlying mitochondrial segregation in yeast also operate in other cell types.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 52 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 31%
Researcher 7 13%
Student > Bachelor 6 12%
Student > Master 6 12%
Student > Doctoral Student 3 6%
Other 5 10%
Unknown 9 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 28 54%
Agricultural and Biological Sciences 6 12%
Neuroscience 2 4%
Business, Management and Accounting 1 2%
Immunology and Microbiology 1 2%
Other 4 8%
Unknown 10 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 January 2018.
All research outputs
#14,963,216
of 23,015,156 outputs
Outputs from Frontiers in Cell and Developmental Biology
#3,238
of 9,116 outputs
Outputs of similar age
#256,246
of 442,237 outputs
Outputs of similar age from Frontiers in Cell and Developmental Biology
#20
of 39 outputs
Altmetric has tracked 23,015,156 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 9,116 research outputs from this source. They receive a mean Attention Score of 3.4. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 442,237 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.