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Single Cell Multi-Omics Technology: Methodology and Application

Overview of attention for article published in Frontiers in Cell and Developmental Biology, April 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

twitter
8 X users
patent
2 patents
wikipedia
3 Wikipedia pages

Citations

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141 Dimensions

Readers on

mendeley
423 Mendeley
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Title
Single Cell Multi-Omics Technology: Methodology and Application
Published in
Frontiers in Cell and Developmental Biology, April 2018
DOI 10.3389/fcell.2018.00028
Pubmed ID
Authors

Youjin Hu, Qin An, Katherine Sheu, Brandon Trejo, Shuxin Fan, Ying Guo

Abstract

In the era of precision medicine, multi-omics approaches enable the integration of data from diverse omics platforms, providing multi-faceted insight into the interrelation of these omics layers on disease processes. Single cell sequencing technology can dissect the genotypic and phenotypic heterogeneity of bulk tissue and promises to deepen our understanding of the underlying mechanisms governing both health and disease. Through modification and combination of single cell assays available for transcriptome, genome, epigenome, and proteome profiling, single cell multi-omics approaches have been developed to simultaneously and comprehensively study not only the unique genotypic and phenotypic characteristics of single cells, but also the combined regulatory mechanisms evident only at single cell resolution. In this review, we summarize the state-of-the-art single cell multi-omics methods and discuss their applications, challenges, and future directions.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 423 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 423 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 88 21%
Researcher 69 16%
Student > Master 45 11%
Student > Bachelor 37 9%
Student > Doctoral Student 18 4%
Other 54 13%
Unknown 112 26%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 138 33%
Agricultural and Biological Sciences 45 11%
Computer Science 26 6%
Engineering 14 3%
Medicine and Dentistry 13 3%
Other 62 15%
Unknown 125 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 November 2023.
All research outputs
#2,508,142
of 25,808,886 outputs
Outputs from Frontiers in Cell and Developmental Biology
#434
of 10,582 outputs
Outputs of similar age
#50,229
of 341,704 outputs
Outputs of similar age from Frontiers in Cell and Developmental Biology
#3
of 34 outputs
Altmetric has tracked 25,808,886 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 10,582 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,704 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.