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Adenosine A2B Receptor: From Cell Biology to Human Diseases

Overview of attention for article published in Frontiers in Chemistry, August 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

blogs
1 blog
twitter
4 X users

Citations

dimensions_citation
74 Dimensions

Readers on

mendeley
287 Mendeley
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Title
Adenosine A2B Receptor: From Cell Biology to Human Diseases
Published in
Frontiers in Chemistry, August 2016
DOI 10.3389/fchem.2016.00037
Pubmed ID
Authors

Ying Sun, Pingbo Huang

Abstract

Extracellular adenosine is a ubiquitous signaling molecule that modulates a wide array of biological processes. Recently, significant advances have been made in our understanding of A2B adenosine receptor (A2BAR). In this review, we first summarize some of the general characteristics of A2BAR, and then we describe the multiple binding partners of the receptor, such as newly identified α-actinin-1 and p105, and discuss how these associated proteins could modulate A2BAR's functions, including certain seemingly paradoxical functions of the receptor. Growing evidence indicates a critical role of A2BAR in cancer, renal disease, and diabetes, in addition to its importance in the regulation of vascular diseases, and lung disease. Here, we also discuss the role of A2BAR in cancer, renal disease, and diabetes and the potential of the receptor as a target for treating these three diseases.

X Demographics

X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 287 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 287 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 123 43%
Researcher 21 7%
Student > Master 18 6%
Student > Ph. D. Student 16 6%
Student > Doctoral Student 9 3%
Other 12 4%
Unknown 88 31%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 87 30%
Biochemistry, Genetics and Molecular Biology 49 17%
Agricultural and Biological Sciences 14 5%
Chemistry 13 5%
Medicine and Dentistry 10 3%
Other 17 6%
Unknown 97 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 June 2021.
All research outputs
#3,618,995
of 22,883,326 outputs
Outputs from Frontiers in Chemistry
#224
of 5,968 outputs
Outputs of similar age
#62,647
of 341,487 outputs
Outputs of similar age from Frontiers in Chemistry
#2
of 9 outputs
Altmetric has tracked 22,883,326 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,968 research outputs from this source. They receive a mean Attention Score of 2.0. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,487 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 7 of them.