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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Quinone-Derived π-Extended Phenazines as New Fluorogenic Probes for Live-Cell Imaging of Lipid Droplets
|
|---|---|
| Published in |
Frontiers in Chemistry, August 2018
|
| DOI | 10.3389/fchem.2018.00339 |
| Pubmed ID | |
| Authors |
Fabio de Moliner, Aaron King, Gleiston G. Dias, Guilherme F. de Lima, Carlos A. de Simone, Eufrânio N. da Silva Júnior, Marc Vendrell |
| Abstract |
We describe a new synthetic methodology for the preparation of fluorescent π-extended phenazines from the naturally-occurring naphthoquinone lapachol. These novel structures represent the first fluorogenic probes based on the phenazine scaffold for imaging of lipid droplets in live cells. Systematic characterization and analysis of the compounds in vitro and in cells led to the identification of key structural features responsible for the fluorescent behavior of quinone-derived π-extended phenazines. Furthermore, live-cell imaging experiments identified one compound (P1) as a marker for intracellular lipid droplets with minimal background and enhanced performance over the lipophilic tracker Nile Red. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 25% |
| Korea, Republic of | 1 | 8% |
| Unknown | 8 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 7 | 58% |
| Members of the public | 4 | 33% |
| Practitioners (doctors, other healthcare professionals) | 1 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 19 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 5 | 26% |
| Other | 2 | 11% |
| Student > Master | 2 | 11% |
| Student > Postgraduate | 2 | 11% |
| Professor | 1 | 5% |
| Other | 3 | 16% |
| Unknown | 4 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 11 | 58% |
| Biochemistry, Genetics and Molecular Biology | 1 | 5% |
| Physics and Astronomy | 1 | 5% |
| Agricultural and Biological Sciences | 1 | 5% |
| Medicine and Dentistry | 1 | 5% |
| Other | 1 | 5% |
| Unknown | 3 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 August 2018.
All research outputs
#5,838,828
of 23,798,792 outputs
Outputs from Frontiers in Chemistry
#382
of 6,260 outputs
Outputs of similar age
#96,965
of 331,982 outputs
Outputs of similar age from Frontiers in Chemistry
#13
of 193 outputs
Altmetric has tracked 23,798,792 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,260 research outputs from this source. They receive a mean Attention Score of 2.1. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 331,982 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 193 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.