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The Escherichia coli Serogroup O1 and O2 Lipopolysaccharides Are Encoded by Multiple O-antigen Gene Clusters

Overview of attention for article published in Frontiers in Cellular and Infection Microbiology, February 2017
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Title
The Escherichia coli Serogroup O1 and O2 Lipopolysaccharides Are Encoded by Multiple O-antigen Gene Clusters
Published in
Frontiers in Cellular and Infection Microbiology, February 2017
DOI 10.3389/fcimb.2017.00030
Pubmed ID
Authors

Sabine Delannoy, Lothar Beutin, Patricia Mariani-Kurkdjian, Aubin Fleiss, Stéphane Bonacorsi, Patrick Fach

Abstract

Escherichia coli strains belonging to serogroups O1 and O2 are frequently associated with human infections, especially extra-intestinal infections such as bloodstream infections or urinary tract infections. These strains can be associated with a large array of flagellar antigens. Because of their frequency and clinical importance, a reliable detection of E. coli O1 and O2 strains and also the frequently associated K1 capsule is important for diagnosis and source attribution of E. coli infections in humans and animals. By sequencing the O-antigen clusters of various O1 and O2 strains we showed that the serogroups O1 and O2 are encoded by different sets of O-antigen encoding genes and identified potentially new O-groups. We developed qPCR-assays to detect the various O1 and O2 variants and the K1-encoding gene. These qPCR assays proved to be 100% sensitive and 100% specific and could be valuable tools for the investigations of zoonotic and food-borne infection of humans with O1 and O2 extra-intestinal (ExPEC) or Shiga toxin-producing E. coli (STEC) strains.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
New Zealand 1 1%
Unknown 66 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 18%
Student > Master 10 15%
Student > Bachelor 9 13%
Researcher 6 9%
Student > Postgraduate 3 4%
Other 9 13%
Unknown 18 27%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 13 19%
Immunology and Microbiology 10 15%
Veterinary Science and Veterinary Medicine 9 13%
Agricultural and Biological Sciences 6 9%
Chemistry 2 3%
Other 7 10%
Unknown 20 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 February 2017.
All research outputs
#20,402,251
of 22,952,268 outputs
Outputs from Frontiers in Cellular and Infection Microbiology
#6,027
of 6,462 outputs
Outputs of similar age
#355,801
of 420,202 outputs
Outputs of similar age from Frontiers in Cellular and Infection Microbiology
#98
of 114 outputs
Altmetric has tracked 22,952,268 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,462 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 420,202 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 114 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.