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Taming Parasites by Tailoring Them

Overview of attention for article published in Frontiers in Cellular and Infection Microbiology, July 2017
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Title
Taming Parasites by Tailoring Them
Published in
Frontiers in Cellular and Infection Microbiology, July 2017
DOI 10.3389/fcimb.2017.00292
Pubmed ID
Authors

Bingjian Ren, Nishith Gupta

Abstract

The next-generation gene editing based on CRISPR (clustered regularly interspaced short palindromic repeats) has been successfully implemented in a wide range of organisms including some protozoan parasites. However, application of such a versatile game-changing technology in molecular parasitology remains fairly underexplored. Here, we briefly introduce state-of-the-art in human and mouse research and usher new directions to drive the parasitology research in the years to come. In precise, we outline contemporary ways to embolden existing apicomplexan and kinetoplastid parasite models by commissioning front-line gene-tailoring methods, and illustrate how we can break the enduring gridlock of gene manipulation in non-model parasitic protists to tackle intriguing questions that remain long unresolved otherwise. We show how a judicious solicitation of the CRISPR technology can eventually balance out the two facets of pathogen-host interplay.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 49 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 10 20%
Student > Ph. D. Student 9 18%
Other 4 8%
Researcher 3 6%
Student > Master 2 4%
Other 5 10%
Unknown 16 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 13 27%
Agricultural and Biological Sciences 6 12%
Immunology and Microbiology 4 8%
Nursing and Health Professions 1 2%
Computer Science 1 2%
Other 8 16%
Unknown 16 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 July 2017.
All research outputs
#14,070,926
of 22,985,065 outputs
Outputs from Frontiers in Cellular and Infection Microbiology
#2,466
of 6,478 outputs
Outputs of similar age
#168,648
of 313,520 outputs
Outputs of similar age from Frontiers in Cellular and Infection Microbiology
#82
of 174 outputs
Altmetric has tracked 22,985,065 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,478 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,520 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 174 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.