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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Use of Digital Droplet PCR to Detect Mycobacterium tuberculosis DNA in Whole Blood-Derived DNA Samples from Patients with Pulmonary and Extrapulmonary Tuberculosis
|
|---|---|
| Published in |
Frontiers in Cellular and Infection Microbiology, August 2017
|
| DOI | 10.3389/fcimb.2017.00369 |
| Pubmed ID | |
| Authors |
Jiaru Yang, Xinlin Han, Aihua Liu, Xiyuan Bai, Cuiping Xu, Fukai Bao, Shi Feng, Lvyan Tao, Mingbiao Ma, Yun Peng |
| Abstract |
Tuberculosis (TB) is a chronic infectious disease that has been threatening public health for many centuries. The clinical diagnostic procedure for TB is time-consuming and laborious. In the last 20 years, real-time fluorescence-based quantitative PCR (real-time PCR) has become a better alternative for TB diagnosis in clinics due to its sensitivity and specificity. Recently, digital droplet PCR (ddPCR) has been developed, and it might be an ideal alternative to conventional real-time PCR for microorganism detection. In this study, we aimed to assess the capacity of ddPCR and real-time PCR for detecting low levels of circulating Mycobacterium tuberculosis (MTB) DNA. The study involved testing whole blood samples for an MTB DNA target (known as IS6110). Blood samples were obtained from 28 patients with pulmonary TB, 28 patients with extrapulmonary TB, and 28 healthy individuals. The results show that ddPCR could be used to measure low levels of MTB DNA, and it has the potential to be used to diagnose pulmonary and extrapulmonary TB based on clinical samples. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 50% |
| Unknown | 2 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 83 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 13% |
| Researcher | 9 | 11% |
| Student > Master | 8 | 10% |
| Student > Bachelor | 7 | 8% |
| Student > Doctoral Student | 6 | 7% |
| Other | 15 | 18% |
| Unknown | 27 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 16 | 19% |
| Medicine and Dentistry | 8 | 10% |
| Veterinary Science and Veterinary Medicine | 6 | 7% |
| Immunology and Microbiology | 5 | 6% |
| Agricultural and Biological Sciences | 4 | 5% |
| Other | 12 | 14% |
| Unknown | 32 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 August 2017.
All research outputs
#14,951,544
of 22,997,544 outputs
Outputs from Frontiers in Cellular and Infection Microbiology
#3,259
of 6,496 outputs
Outputs of similar age
#188,591
of 318,510 outputs
Outputs of similar age from Frontiers in Cellular and Infection Microbiology
#78
of 129 outputs
Altmetric has tracked 22,997,544 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,496 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 318,510 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 129 others from the same source and published within six weeks on either side of this one. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.