Title |
Type VI Secretion Systems Present New Insights on Pathogenic Yersinia
|
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Published in |
Frontiers in Cellular and Infection Microbiology, July 2018
|
DOI | 10.3389/fcimb.2018.00260 |
Pubmed ID | |
Authors |
Xiaobing Yang, Junfeng Pan, Yao Wang, Xihui Shen |
Abstract |
The type VI secretion system (T6SS) is a versatile secretion system widely distributed in Gram-negative bacteria that delivers multiple effector proteins into either prokaryotic or eukaryotic cells, or into the extracellular milieu. T6SS participates in various physiological processes including bacterial competition, host infection, and stress response. Three pathogenic Yersinia species, namely Yersinia pestis, Yersinia pseudotuberculosis, and Yersinia enterocolitica, possess different copies of T6SSs with distinct biological functions. This review summarizes the pathogenic, antibacterial, and stress-resistant roles of T6SS in Yersinia and the ion-transporting ability in Y. pseudotuberculosis. In addition, the T6SS-related effectors and regulators identified in Yersinia are discussed. |
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Mendeley readers
Geographical breakdown
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Unknown | 91 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 15 | 16% |
Student > Ph. D. Student | 14 | 15% |
Student > Master | 12 | 13% |
Researcher | 10 | 11% |
Student > Doctoral Student | 6 | 7% |
Other | 7 | 8% |
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Mathematics | 1 | 1% |
Other | 7 | 8% |
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