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High-Sensitivity C-Reactive Protein is Related to Central Obesity and the Number of Metabolic Syndrome Components in Jamaican Young Adults

Overview of attention for article published in Frontiers in Cardiovascular Medicine, December 2014
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Title
High-Sensitivity C-Reactive Protein is Related to Central Obesity and the Number of Metabolic Syndrome Components in Jamaican Young Adults
Published in
Frontiers in Cardiovascular Medicine, December 2014
DOI 10.3389/fcvm.2014.00012
Pubmed ID
Authors

Nadia R. Bennett, Trevor S. Ferguson, Franklyn I. Bennett, Marshall K. Tulloch-Reid, Novie O. M. Younger-Coleman, Maria D. Jackson, Maureen E. Samms-Vaughan, Rainford J. Wilks

Abstract

High-sensitivity C-reactive protein (hsCRP) has been shown to predict cardiovascular disease (CVD) endpoints and is associated with CVD risk factors and the metabolic syndrome. This study evaluated the association between hsCRP and CVD risk factors among Afro-Caribbean young adults in Jamaica. We conducted a cross-sectional analysis of data from the Jamaica 1986 Birth Cohort Study. Data were collected between 2005 and 2007 when participants were 18-20 years old. All participants completed an interviewer administered questionnaire and had anthropometric and blood pressure (BP) measurements performed. Fasting blood samples were collected for measurement of glucose, lipids, and hsCRP. Logistic regression models were used to identify factors independently associated with high hsCRP. Analyses included 342 men and 404 women with mean age 18.8 ± 0.6 years. Approximately 15% of the participants had high risk hsCRP (>3 mg/L), with a higher prevalence among women (20 vs. 9%; p < 0.001). The prevalence of elevated hsCRP increased with body mass index category, high waist circumference (WC), high triglycerides, low high density lipoprotein, and lower parental education among women, but only for high WC and lower parental education among men. In logistic regression models controlling for sex and parental education, high WC was associated with significantly higher odds of high hsCRP (OR 7.8, 95% CI 4.8-12.9, p < 0.001). In a similar model, high hsCRP was also associated with the number of metabolic syndrome components. Compared to participants with no metabolic syndrome component, having one metabolic syndrome component was associated with a twofold higher odds of high hsCRP (OR 2.2, 95% CI 1.3-3.8, p = 0.005), while having three components was associated with a 14-fold higher odds of high hsCRP (OR 13.5, 95% CI 2.4-76.0, p < 0.001). High hsCRP is common among Jamaican young adults and is strongly associated with central obesity and the number of metabolic syndrome components.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 42 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 12%
Student > Bachelor 4 10%
Student > Master 4 10%
Student > Doctoral Student 3 7%
Professor 3 7%
Other 8 19%
Unknown 15 36%
Readers by discipline Count As %
Medicine and Dentistry 9 21%
Nursing and Health Professions 7 17%
Biochemistry, Genetics and Molecular Biology 2 5%
Arts and Humanities 1 2%
Sports and Recreations 1 2%
Other 1 2%
Unknown 21 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 December 2014.
All research outputs
#13,417,604
of 22,772,779 outputs
Outputs from Frontiers in Cardiovascular Medicine
#1,584
of 6,665 outputs
Outputs of similar age
#173,776
of 354,364 outputs
Outputs of similar age from Frontiers in Cardiovascular Medicine
#2
of 10 outputs
Altmetric has tracked 22,772,779 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,665 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 354,364 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 8 of them.