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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Inflammation in Vein Graft Disease
|
|---|---|
| Published in |
Frontiers in Cardiovascular Medicine, January 2018
|
| DOI | 10.3389/fcvm.2018.00003 |
| Pubmed ID | |
| Authors |
Margreet R. de Vries, Paul H. A. Quax |
| Abstract |
Bypass surgery is one of the most frequently used strategies to revascularize tissues downstream occlusive atherosclerotic lesions. For venous bypass surgery the great saphenous vein is the most commonly used vessel. Unfortunately, graft efficacy is low due to the development of vascular inflammation, intimal hyperplasia and accelerated atherosclerosis. Moreover, failure of grafts leads to significant adverse outcomes and even mortality. The last couple of decades not much has changed in the treatment of vein graft disease (VGD). However, insight is the cellular and molecular mechanisms of VGD has increased. In this review, we discuss the latest insights on VGD and the role of inflammation in this. We discuss vein graft pathophysiology including hemodynamic changes, the role of vessel wall constitutions and vascular remodeling. We show that profound systemic and local inflammatory responses, including inflammation of the perivascular fat, involve both the innate and adaptive immune system. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 70 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 10 | 14% |
| Student > Ph. D. Student | 9 | 13% |
| Student > Postgraduate | 6 | 9% |
| Student > Master | 6 | 9% |
| Student > Doctoral Student | 5 | 7% |
| Other | 11 | 16% |
| Unknown | 23 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 20 | 29% |
| Engineering | 7 | 10% |
| Biochemistry, Genetics and Molecular Biology | 5 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 6% |
| Immunology and Microbiology | 1 | 1% |
| Other | 6 | 9% |
| Unknown | 27 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 February 2018.
All research outputs
#15,439,008
of 26,184,649 outputs
Outputs from Frontiers in Cardiovascular Medicine
#2,024
of 9,455 outputs
Outputs of similar age
#235,642
of 455,462 outputs
Outputs of similar age from Frontiers in Cardiovascular Medicine
#14
of 27 outputs
Altmetric has tracked 26,184,649 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 9,455 research outputs from this source. They receive a mean Attention Score of 4.5. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 455,462 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.