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The Role of Platelet Microparticle Associated microRNAs in Cellular Crosstalk

Overview of attention for article published in Frontiers in Cardiovascular Medicine, April 2018
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Title
The Role of Platelet Microparticle Associated microRNAs in Cellular Crosstalk
Published in
Frontiers in Cardiovascular Medicine, April 2018
DOI 10.3389/fcvm.2018.00029
Pubmed ID
Authors

Luoxing Xia, Zhi Zeng, Wai Ho Tang

Abstract

Platelet is an anucleate cell containing abundant messenger RNAs and microRNAs (miRNAs), and their functional roles in hemostasis and inflammation remain elusive. Accumulating evidence has suggested that platelets can actively transfer RNAs to hepatocytes, vascular cells, macrophages, and tumor cells. The incorporated mRNAs are translated into proteins, and miRNAs were found to regulate the gene expression, resulting in the functional change of the recipient cells. This novel intercellular communication opens up a new avenue for the pathophysiological role of platelet in platelet-associated vascular diseases. Therefore, understanding the underlying mechanism and identification of the platelet miRNAs involved in this biological process would provide novel diagnostic and therapeutic targets for cardiovascular diseases.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 39 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 23%
Student > Ph. D. Student 7 18%
Student > Doctoral Student 4 10%
Student > Bachelor 3 8%
Student > Master 3 8%
Other 8 21%
Unknown 5 13%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 11 28%
Medicine and Dentistry 9 23%
Pharmacology, Toxicology and Pharmaceutical Science 2 5%
Arts and Humanities 2 5%
Immunology and Microbiology 2 5%
Other 4 10%
Unknown 9 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 April 2018.
All research outputs
#17,939,682
of 23,035,022 outputs
Outputs from Frontiers in Cardiovascular Medicine
#2,844
of 6,945 outputs
Outputs of similar age
#239,067
of 329,119 outputs
Outputs of similar age from Frontiers in Cardiovascular Medicine
#27
of 35 outputs
Altmetric has tracked 23,035,022 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,945 research outputs from this source. They receive a mean Attention Score of 4.2. This one has gotten more attention than average, scoring higher than 53% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,119 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.