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Cardiotonic Steroids as Modulators of Neuroinflammation

Overview of attention for article published in Frontiers in endocrinology, February 2016
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Title
Cardiotonic Steroids as Modulators of Neuroinflammation
Published in
Frontiers in endocrinology, February 2016
DOI 10.3389/fendo.2016.00010
Pubmed ID
Authors

Ana Maria Orellana, Paula Fernanda Kinoshita, Jacqueline Alves Leite, Elisa Mitiko Kawamoto, Cristoforo Scavone

Abstract

Cardiotonic steroids (CTS) are a class of specific ligands of the Na(+), K(+)- ATPase (NKA). NKA is a P-type ATPase that is ubiquitously expressed and although well known to be responsible for the maintenance of the cell electrochemical gradient through active transport, NKA can also act as a signal transducer in the presence of CTS. Inflammation, in addition to importantly driving organism defense and survival mechanisms, can also modulate NKA activity and memory formation, as well as being relevant to many chronic illnesses, neurodegenerative diseases, and mood disorders. The aim of the current review is to highlight the recent advances as to the role of CTS and NKA in inflammatory process, with a particular focus in the central nervous system.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 1%
Unknown 67 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 9 13%
Student > Master 7 10%
Researcher 6 9%
Student > Ph. D. Student 6 9%
Student > Doctoral Student 5 7%
Other 14 21%
Unknown 21 31%
Readers by discipline Count As %
Neuroscience 8 12%
Biochemistry, Genetics and Molecular Biology 8 12%
Medicine and Dentistry 7 10%
Agricultural and Biological Sciences 6 9%
Immunology and Microbiology 4 6%
Other 13 19%
Unknown 22 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 February 2016.
All research outputs
#21,110,894
of 25,932,719 outputs
Outputs from Frontiers in endocrinology
#6,928
of 13,317 outputs
Outputs of similar age
#231,925
of 312,758 outputs
Outputs of similar age from Frontiers in endocrinology
#28
of 36 outputs
Altmetric has tracked 25,932,719 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,317 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
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We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one is in the 2nd percentile – i.e., 2% of its contemporaries scored the same or lower than it.