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Primary Hypothyroidism with Markedly High Prolactin

Overview of attention for article published in Frontiers in endocrinology, April 2016
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3 X users
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1 Facebook page
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1 YouTube creator

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Title
Primary Hypothyroidism with Markedly High Prolactin
Published in
Frontiers in endocrinology, April 2016
DOI 10.3389/fendo.2016.00035
Pubmed ID
Authors

Mohd Saleem Ansari, Mussa H. Almalki

Abstract

Secondary pituitary enlargement due to primary hypothyroidism is not a common manifestation. The loss of thyroxin feedback inhibition in primary hypothyroidism causes overproduction of thyrotropin-releasing-hormone (TRH), which results in secondary pituitary enlargement. TRH has a weak stimulatory effect on the lactotroph cells of the pituitary, so a mild to moderate increase in prolactin (PRL) levels is expected. We report the case of a 67-year-old female who presented with a large pituitary mass and a very high level of TSH in association with a significant rise in PRL level. In this case, diagnosing a sellar mass was challenging; it was difficult to distinguish between pituitary prolactinoma and primary hypothyroidism with secondary pituitary hyperplasia. Thyroid hormone replacement proved that this patient's hyperprolactinemia was due to hyperplasia of the pituitary gland. As such, making the correct diagnosis and initiating thyroid hormone therapy can prevent unnecessary treatment with dopamine agonists.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 40 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 15%
Student > Bachelor 6 15%
Student > Doctoral Student 4 10%
Professor > Associate Professor 2 5%
Student > Master 2 5%
Other 4 10%
Unknown 16 40%
Readers by discipline Count As %
Medicine and Dentistry 7 18%
Biochemistry, Genetics and Molecular Biology 4 10%
Neuroscience 3 8%
Agricultural and Biological Sciences 2 5%
Nursing and Health Professions 2 5%
Other 7 18%
Unknown 15 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 August 2022.
All research outputs
#15,237,808
of 25,870,940 outputs
Outputs from Frontiers in endocrinology
#3,188
of 13,300 outputs
Outputs of similar age
#155,189
of 313,537 outputs
Outputs of similar age from Frontiers in endocrinology
#10
of 36 outputs
Altmetric has tracked 25,870,940 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,300 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,537 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.