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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The Potential Role of Contraction-Induced Myokines in the Regulation of Metabolic Function for the Prevention and Treatment of Type 2 Diabetes
|
|---|---|
| Published in |
Frontiers in endocrinology, May 2017
|
| DOI | 10.3389/fendo.2017.00097 |
| Pubmed ID | |
| Authors |
Brian P. Carson |
| Abstract |
Skeletal muscle represents the largest organ in the body, comprises 36-42% of body weight, and has recently been recognized as having an endocrine function. Proteins expressed and released by muscle that have autocrine, paracrine, and endocrine bioactivities have been termed myokines. It is likely that muscle contraction represents the primary stimulus for the synthesis and secretion of myokines to enable communication with other organs such as the liver, adipose tissue, brain, and auto-regulation of muscle metabolism. To date, several hundred myokines in the muscle secretome have been identified, a sub-population of which are specifically induced by skeletal muscle contraction. However, the bioactivity of many of these myokines and the mechanism through which they act has either not yet been characterized or remains poorly understood. Physical activity and exercise are recognized as a central tenet in both the prevention and treatment of type 2 diabetes (T2D). Recent data suggest humoral factors such as muscle-derived secretory proteins may mediate the beneficial effects of exercise in the treatment of metabolic diseases. This mini-review aims to summarize our current knowledge on the role of contraction-induced myokines in mediating the beneficial effects of physical activity and exercise in the prevention and treatment of T2D, specifically glucose and lipid metabolism. Future directions as to how we can optimize contraction-induced myokine secretion to inform exercise protocols for the prevention and treatment of T2D will also be discussed. |
X Demographics
The data shown below were collected from the profiles of 22 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Ireland | 4 | 18% |
| Spain | 3 | 14% |
| United States | 2 | 9% |
| Argentina | 1 | 5% |
| Grenada | 1 | 5% |
| United Kingdom | 1 | 5% |
| Switzerland | 1 | 5% |
| Canada | 1 | 5% |
| Unknown | 8 | 36% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 18 | 82% |
| Practitioners (doctors, other healthcare professionals) | 2 | 9% |
| Scientists | 2 | 9% |
Mendeley readers
The data shown below were compiled from readership statistics for 134 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 134 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 19 | 14% |
| Student > Ph. D. Student | 18 | 13% |
| Student > Bachelor | 18 | 13% |
| Researcher | 8 | 6% |
| Student > Doctoral Student | 6 | 4% |
| Other | 21 | 16% |
| Unknown | 44 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Sports and Recreations | 23 | 17% |
| Medicine and Dentistry | 20 | 15% |
| Biochemistry, Genetics and Molecular Biology | 15 | 11% |
| Nursing and Health Professions | 8 | 6% |
| Agricultural and Biological Sciences | 4 | 3% |
| Other | 11 | 8% |
| Unknown | 53 | 40% |
Attention Score in Context
This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 June 2020.
All research outputs
#2,328,459
of 25,382,440 outputs
Outputs from Frontiers in endocrinology
#618
of 13,018 outputs
Outputs of similar age
#42,577
of 324,903 outputs
Outputs of similar age from Frontiers in endocrinology
#5
of 84 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,018 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,903 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 84 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.