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One-third of an Archivial Series of Papillary Thyroid Cancer (Years 2007–2015) Has Coexistent Chronic Lymphocytic Thyroiditis, Which Is Associated with a More Favorable Tumor-Node-Metastasis Staging

Overview of attention for article published in Frontiers in endocrinology, December 2017
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Title
One-third of an Archivial Series of Papillary Thyroid Cancer (Years 2007–2015) Has Coexistent Chronic Lymphocytic Thyroiditis, Which Is Associated with a More Favorable Tumor-Node-Metastasis Staging
Published in
Frontiers in endocrinology, December 2017
DOI 10.3389/fendo.2017.00337
Pubmed ID
Authors

Antonio Ieni, Roberto Vita, Emilia Magliolo, Mariacarmela Santarpia, Flavia Di Bari, Salvatore Benvenga, Giovanni Tuccari

Abstract

The significance and impact of the coexistence of chronic lymphocytic thyroiditis (CLT) with thyroid cancer is still debated. To verify the influence of CLT on papillary thyroid cancer (PTC), we retrospectively collected 505 PTC cases and analyzed age at diagnosis, sex, size, lymph node status, and staging. We found that CLT was present in 168 PTC (33.3%). Compared with the 337 patients without CLT (non-CLT), CLT patients were younger (44.42 ± 13.72 vs. 47.21 ± 13.76 years, P = 0.03), had smaller tumors (9.39 ± 6.10 vs. 12 ± 9.71 mm, P = 0.002), and lower rate of lymph node metastases (12.5 vs. 21.96%, P = 0.01, OR = 0.508). Tumor-node-metastasis (TNM) staging (T1a through T4) was more favorable for the CLT group compared to the non-CLT group (for instance, T1a = 65.5 vs. 49.8%, T3 = 4.8 vs. 23.4%). This study shows that one in three patients with PTC harbors CLT, which is associated with a more favorable TNM staging, consistently with a favorable outlook of PTC.

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Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 40%
Student > Bachelor 3 15%
Researcher 2 10%
Student > Ph. D. Student 2 10%
Other 1 5%
Other 1 5%
Unknown 3 15%
Readers by discipline Count As %
Medicine and Dentistry 11 55%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Physics and Astronomy 1 5%
Earth and Planetary Sciences 1 5%
Unknown 6 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 December 2017.
All research outputs
#22,764,772
of 25,382,440 outputs
Outputs from Frontiers in endocrinology
#8,338
of 13,021 outputs
Outputs of similar age
#384,359
of 444,941 outputs
Outputs of similar age from Frontiers in endocrinology
#70
of 104 outputs
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So far Altmetric has tracked 13,021 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 104 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.