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Long non-coding RNA-dependent transcriptional regulation in neuronal development and disease

Overview of attention for article published in Frontiers in Genetics, June 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

twitter
8 X users
peer_reviews
1 peer review site
googleplus
1 Google+ user

Citations

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138 Dimensions

Readers on

mendeley
230 Mendeley
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Title
Long non-coding RNA-dependent transcriptional regulation in neuronal development and disease
Published in
Frontiers in Genetics, June 2014
DOI 10.3389/fgene.2014.00164
Pubmed ID
Authors

Brian S. Clark, Seth Blackshaw

Abstract

Comprehensive analysis of the mammalian transcriptome has revealed that long non-coding RNAs (lncRNAs) may make up a large fraction of cellular transcripts. Recent years have seen a surge of studies aimed at functionally characterizing the role of lncRNAs in development and disease. In this review, we discuss new findings implicating lncRNAs in controlling development of the central nervous system (CNS). The evolution of the higher vertebrate brain has been accompanied by an increase in the levels and complexities of lncRNAs expressed within the developing nervous system. Although a limited number of CNS-expressed lncRNAs are now known to modulate the activity of proteins important for neuronal differentiation, the function of the vast majority of neuronal-expressed lncRNAs is still unknown. Topics of intense current interest include the mechanism by which CNS-expressed lncRNAs might function in epigenetic and transcriptional regulation during neuronal development, and how gain and loss of function of individual lncRNAs contribute to neurological diseases.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 230 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 <1%
Germany 1 <1%
Italy 1 <1%
Brazil 1 <1%
India 1 <1%
Netherlands 1 <1%
China 1 <1%
United Kingdom 1 <1%
Japan 1 <1%
Other 1 <1%
Unknown 219 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 57 25%
Researcher 55 24%
Student > Master 21 9%
Student > Bachelor 19 8%
Student > Doctoral Student 14 6%
Other 41 18%
Unknown 23 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 88 38%
Biochemistry, Genetics and Molecular Biology 67 29%
Medicine and Dentistry 16 7%
Neuroscience 15 7%
Computer Science 4 2%
Other 9 4%
Unknown 31 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 July 2014.
All research outputs
#4,480,599
of 22,757,090 outputs
Outputs from Frontiers in Genetics
#1,371
of 11,758 outputs
Outputs of similar age
#44,525
of 228,645 outputs
Outputs of similar age from Frontiers in Genetics
#23
of 124 outputs
Altmetric has tracked 22,757,090 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,758 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,645 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 124 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.