↓ Skip to main content

Disrupted human–pathogen co-evolution: a model for disease

Overview of attention for article published in Frontiers in Genetics, August 2014
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

blogs
1 blog
twitter
23 X users
facebook
1 Facebook page
googleplus
1 Google+ user

Citations

dimensions_citation
52 Dimensions

Readers on

mendeley
134 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Disrupted human–pathogen co-evolution: a model for disease
Published in
Frontiers in Genetics, August 2014
DOI 10.3389/fgene.2014.00290
Pubmed ID
Authors

Nuri Kodaman, Rafal S. Sobota, Robertino Mera, Barbara G. Schneider, Scott M. Williams

Abstract

A major goal in infectious disease research is to identify the human and pathogenic genetic variants that explain differences in microbial pathogenesis. However, neither pathogenic strain nor human genetic variation in isolation has proven adequate to explain the heterogeneity of disease pathology. We suggest that disrupted co-evolution between a pathogen and its human host can explain variation in disease outcomes, and that genome-by-genome interactions should therefore be incorporated into genetic models of disease caused by infectious agents. Genetic epidemiological studies that fail to take both the pathogen and host into account can lead to false and misleading conclusions about disease etiology. We discuss our model in the context of three pathogens, Helicobacter pylori, Mycobacterium tuberculosis and human papillomavirus, and generalize the conditions under which it may be applicable.

X Demographics

X Demographics

The data shown below were collected from the profiles of 23 X users who shared this research output. Click here to find out more about how the information was compiled.
As of 1 July 2024, you may notice a temporary increase in the numbers of X profiles with Unknown location. Click here to learn more.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 134 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 2%
Canada 2 1%
Germany 1 <1%
Italy 1 <1%
Colombia 1 <1%
Brazil 1 <1%
Russia 1 <1%
Mexico 1 <1%
Unknown 123 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 30 22%
Researcher 18 13%
Student > Master 17 13%
Student > Bachelor 16 12%
Student > Doctoral Student 11 8%
Other 20 15%
Unknown 22 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 44 33%
Biochemistry, Genetics and Molecular Biology 25 19%
Medicine and Dentistry 13 10%
Immunology and Microbiology 10 7%
Social Sciences 6 4%
Other 9 7%
Unknown 27 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 24. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 July 2019.
All research outputs
#1,694,663
of 26,374,136 outputs
Outputs from Frontiers in Genetics
#334
of 13,900 outputs
Outputs of similar age
#16,564
of 248,323 outputs
Outputs of similar age from Frontiers in Genetics
#4
of 132 outputs
Altmetric has tracked 26,374,136 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,900 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 248,323 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 132 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.