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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Insertion of Retrotransposons at Chromosome Ends: Adaptive Response to Chromosome Maintenance
|
|---|---|
| Published in |
Frontiers in Genetics, January 2016
|
| DOI | 10.3389/fgene.2015.00358 |
| Pubmed ID | |
| Authors |
Geraldine Servant, Prescott L Deininger |
| Abstract |
The telomerase complex is a specialized reverse transcriptase (RT) that inserts tandem DNA arrays at the linear chromosome ends and contributes to the protection of the genetic information in eukaryotic genomes. Telomerases are phylogenetically related to retrotransposons, encoding also the RT activity required for the amplification of their sequences throughout the genome. Intriguingly the telomerase gene is lost from the Drosophila genome and tandem retrotransposons replace telomeric sequences at the chromosome extremities. This observation suggests the versatility of RT activity in counteracting the chromosome shortening associated with genome replication and that retrotransposons can provide this activity in case of a dysfunctional telomerase. In this review paper, we describe the major classes of retroelements present in eukaryotic genomes in order to point out the differences and similarities with the telomerase complex. In a second part, we discuss the insertion of retroelements at the ends of chromosomes as an adaptive response for dysfunctional telomeres. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 25% |
| Switzerland | 1 | 25% |
| Unknown | 2 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Czechia | 1 | 1% |
| France | 1 | 1% |
| Unknown | 69 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 14 | 19% |
| Researcher | 13 | 18% |
| Student > Bachelor | 11 | 15% |
| Student > Master | 8 | 11% |
| Student > Doctoral Student | 5 | 7% |
| Other | 7 | 10% |
| Unknown | 14 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 26 | 36% |
| Agricultural and Biological Sciences | 23 | 32% |
| Medicine and Dentistry | 6 | 8% |
| Mathematics | 1 | 1% |
| Computer Science | 1 | 1% |
| Other | 1 | 1% |
| Unknown | 14 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 November 2023.
All research outputs
#3,382,430
of 25,383,225 outputs
Outputs from Frontiers in Genetics
#966
of 13,654 outputs
Outputs of similar age
#55,035
of 404,020 outputs
Outputs of similar age from Frontiers in Genetics
#12
of 55 outputs
Altmetric has tracked 25,383,225 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,654 research outputs from this source. They receive a mean Attention Score of 3.8. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 404,020 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 55 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.