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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Epigenetic Regulation of Cellular Senescence and Aging
|
|---|---|
| Published in |
Frontiers in Genetics, September 2017
|
| DOI | 10.3389/fgene.2017.00138 |
| Pubmed ID | |
| Authors |
Corinne Sidler, Olga Kovalchuk, Igor Kovalchuk |
| Abstract |
Aging is characterized by functional decline of diverse organs and an increased risk for several diseases. Therefore, a high interest exists in understanding the molecular mechanisms that stimulate aging at all levels, from cells and tissues to organs and organisms, in order to develop ways to promote healthy aging. While many molecular and biochemical mechanisms are already understood in some detail, the role of changes in epigenetic regulation has only begun to be considered in recent years. The age-dependent global reduction in heterochromatin, along with site-specific changes in the patterns of DNA methylation and modification of histones, have been observed in several aging model systems. However, understanding of the precise role of such changes requires further research. In this review, we will discuss the role of epigenetic regulation in aging and indicate future research directions that will help elucidate the mechanistic details of it. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 17% |
| Switzerland | 1 | 17% |
| United States | 1 | 17% |
| Unknown | 3 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 180 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 180 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 32 | 18% |
| Student > Bachelor | 29 | 16% |
| Student > Ph. D. Student | 25 | 14% |
| Student > Master | 18 | 10% |
| Student > Doctoral Student | 12 | 7% |
| Other | 21 | 12% |
| Unknown | 43 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 65 | 36% |
| Agricultural and Biological Sciences | 33 | 18% |
| Medicine and Dentistry | 10 | 6% |
| Neuroscience | 6 | 3% |
| Immunology and Microbiology | 5 | 3% |
| Other | 12 | 7% |
| Unknown | 49 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 December 2017.
All research outputs
#13,335,574
of 23,003,906 outputs
Outputs from Frontiers in Genetics
#2,999
of 12,064 outputs
Outputs of similar age
#156,556
of 320,403 outputs
Outputs of similar age from Frontiers in Genetics
#35
of 70 outputs
Altmetric has tracked 23,003,906 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 12,064 research outputs from this source. They receive a mean Attention Score of 3.7. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,403 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 70 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.