Title |
Epigenetics in the Eye: An Overview of the Most Relevant Ocular Diseases
|
---|---|
Published in |
Frontiers in Genetics, October 2017
|
DOI | 10.3389/fgene.2017.00144 |
Pubmed ID | |
Authors |
Hanan A. Alkozi, Rafael Franco, Jesús J. Pintor |
Abstract |
Sight for mammals is one of the most appreciated senses. In humans there are several factors that contribute to the increment in all kind of eye diseases. This mini-review will focus on some diseases whose prevalence is steadily increasing year after year for non-genetic reasons, namely cataracts, dry eye, and glaucoma. Aging, diet, inflammation, drugs, oxidative stress, seasonal and circadian style-of-live changes are impacting on disease prevalence by epigenetics factors, defined as stable heritable traits that are not explained by changes in DNA sequence. The mini-review will concisely show the data showing epigenetics marks in these diseases and on how knowledge on the epigenetic alterations may guide therapeutic approaches to have a healthy eye. |
X Demographics
As of 1 July 2024, you may notice a temporary increase in the numbers of X profiles with Unknown location. Click here to learn more.
Geographical breakdown
Country | Count | As % |
---|---|---|
Austria | 1 | 33% |
United States | 1 | 33% |
Switzerland | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 60 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 8 | 13% |
Researcher | 6 | 10% |
Student > Master | 6 | 10% |
Professor | 5 | 8% |
Student > Ph. D. Student | 5 | 8% |
Other | 12 | 20% |
Unknown | 18 | 30% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 13 | 22% |
Biochemistry, Genetics and Molecular Biology | 10 | 17% |
Agricultural and Biological Sciences | 8 | 13% |
Immunology and Microbiology | 3 | 5% |
Nursing and Health Professions | 2 | 3% |
Other | 6 | 10% |
Unknown | 18 | 30% |