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Genetic Architecture of Feeding Behavior and Feed Efficiency in a Duroc Pig Population

Overview of attention for article published in Frontiers in Genetics, June 2018
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Title
Genetic Architecture of Feeding Behavior and Feed Efficiency in a Duroc Pig Population
Published in
Frontiers in Genetics, June 2018
DOI 10.3389/fgene.2018.00220
Pubmed ID
Authors

Rongrong Ding, Ming Yang, Xingwang Wang, Jianping Quan, Zhanwei Zhuang, Shenping Zhou, Shaoyun Li, Zheng Xu, Enqin Zheng, Gengyuan Cai, Dewu Liu, Wen Huang, Jie Yang, Zhenfang Wu

Abstract

Increasing feed efficiency is a major goal of breeders as it can reduce production cost and energy consumption. However, the genetic architecture of feeding behavior and feed efficiency traits remains elusive. To investigate the genetic architecture of feed efficiency in pigs, three feeding behavior traits (daily feed intake, number of daily visits to feeder, and duration of each visit) and two feed efficiency traits (feed conversion ratio and residual feed intake) were considered. We performed genome-wide association studies (GWASs) of the five traits using a population of 1,008 Duroc pigs genotyped with an Illumina Porcine SNP50K BeadChip. A total of 9 genome-wide (P < 1.54E-06) and 35 suggestive (P < 3.08E-05) single nucleotide polymorphisms (SNPs) were detected. Two pleiotropic quantitative trait loci (QTLs) on SSC 1 and SSC 7 were found to affect more than one trait. Markers WU_10.2_7_18377044 and DRGA0001676 are two key SNPs for these two pleiotropic QTLs. Marker WU_10.2_7_18377044 on SSC 7 contributed 2.16 and 2.37% of the observed phenotypic variance for DFI and RFI, respectively. The other SNP DRGA0001676 on SSC 1 explained 3.22 and 5.46% of the observed phenotypic variance for FCR and RFI, respectively. Finally, functions of candidate genes and gene set enrichment analysis indicate that most of the significant pathways are associated with hormonal and digestive gland secretion during feeding. This study advances our understanding of the genetic mechanisms of feeding behavior and feed efficiency traits and provide an opportunity for increasing feeding efficiency using marker-assisted selection or genomic selection in pigs.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 57 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 12 21%
Student > Ph. D. Student 9 16%
Student > Doctoral Student 7 12%
Student > Bachelor 6 11%
Researcher 4 7%
Other 3 5%
Unknown 16 28%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 44%
Veterinary Science and Veterinary Medicine 4 7%
Biochemistry, Genetics and Molecular Biology 4 7%
Nursing and Health Professions 1 2%
Immunology and Microbiology 1 2%
Other 2 4%
Unknown 20 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 September 2018.
All research outputs
#13,619,233
of 23,090,520 outputs
Outputs from Frontiers in Genetics
#3,321
of 12,141 outputs
Outputs of similar age
#168,940
of 328,030 outputs
Outputs of similar age from Frontiers in Genetics
#56
of 130 outputs
Altmetric has tracked 23,090,520 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 12,141 research outputs from this source. They receive a mean Attention Score of 3.7. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 328,030 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 130 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.